Arbaprostil
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Arbaprostil
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CAS No:
55028-70-1
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Formula:
C21H34O5
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Chemical Name:
Arbaprostil
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Synonyms:
Prosta-5,13-dien-1-oic acid,11,15-dihydroxy-15-methyl-9-oxo-,(5Z,11α,13E,15R)-;(5Z,11α,13E,15R)-11,15-Dihydroxy-15-methyl-9-oxoprosta-5,13-dien-1-oic acid;15(R)-Methylprostaglandin E2;Arbaprostil;15(R)-15-Methyl-PGE2;(15R)-15-Methylprostaglandin E2;CU 83;Arbacet;U 42842;15-Methylprostaglandin E2
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CAS No:
Description
A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumors.
Drug Information
Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief. (See all compounds classified as Anti-Ulcer Agents.)
15 Methylprostaglandin E2
Computed Properties
Molecular Weight:366.5
XLogP3:3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:12
Exact Mass:366.24062418
Monoisotopic Mass:366.24062418
Topological Polar Surface Area:94.8
Heavy Atom Count:26
Complexity:511
Defined Atom Stereocenter Count:4
Defined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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