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Cefuroxime pivoxetil

Cefuroxime pivoxetil structure

CAS No:
100680-33-9
Formula:
C23H28N4O11S
Chemical Name:
Cefuroxime pivoxetil
Synonyms:
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-,1-(2-methoxy-2-methyl-1-oxopropoxy)ethyl ester,(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,1-(2-methoxy-2-methyl-1-oxopropoxy)ethyl ester,[6R-[6α,7β(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,1-(2-methoxy-2-methyl-1-oxopropoxy)ethyl ester,(6R,7R)-;CCI 23628;Cefuroxime pivoxetil

Description

Cefuroxime pivoxetil is a carbamate ester and a cephalosporin.|Cefuroxime Pivoxetil is an ester prodrug of cefuroxime, a semisynthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin with antibacterial activity. Cefuroxime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Cefuroxime pivoxetil Basic Attributes

Molecular Weight：

568.55400

Exact Mass：

568.55

UNII：

LR90117565

DSSTox ID：

DTXSID5022776

NCI Thesaurus Code：

C76178

Characteristics

PSA：

228.07000

XLogP3：

1.52880

Density：

1.51g/cm3

Refractive Index：

1.627

Computed Properties

Molecular Weight:568.6
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:14
Exact Mass:568.14752890
Monoisotopic Mass:568.14752890
Topological Polar Surface Area:224
Heavy Atom Count:39
Complexity:1080
Defined Atom Stereocenter Count:2
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Learn More Other Chemicals

Cefuroxime axetil

64544-07-6
Cefuroxime

55268-75-2
Cefuroxime sodium

56238-63-2

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Guide of Cefuroxime pivoxetil

Description
Basic Attributes
Characteristics
Computed Properties
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