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Home > Encyclopedia > FLUORIDE STANDARD

FLUORIDE STANDARD

pharmaceutical raw materials
FLUORIDE STANDARD structure

FLUORIDE STANDARD 

structure
  • CAS No:

    16984-48-8

  • Formula:

    F-

  • Chemical Name:

    FLUORIDE STANDARD

  • Synonyms:

    Fluoride ion(1-);Fluoride(1-);Fluorine, ion;Perfluoride;FLUORIDE ION STANDARD;FLUORIDE STANDARD SOLUTION;FLUORIDE SINGLE COMPONENT STANDARD;FLUORIDE STANDARD

Description

Liquid|Varies depending on specific compound


Fluoride is a halide anion and a monoatomic fluorine. It is a conjugate base of a hydrogen fluoride.|Having a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amounts in water. Its various salt forms and minerals play numerous roles as chemical reagents, industrial chemicals, and commercial products. It also plays an essential physiological role, such as enhancing the resistance profile and strength of the surface tooth enamel.|Fluoride Ion is considered a trace element, fluoride is any combination of elements containing the fluorine atom in the -1 oxidation state (fluoride ion). Due to its reactivity, fluorine is found in nature as fluorine compounds or fluorides. Fluoride inhibits various enzyme systems, erythrocyte glycolysis and binds Ca++, causing anticoagulation and other toxic effects. In addition, fluoride is a mitogen for osteoblasts and stimulates bone formation. (NCI)|Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.


Of the general formula MxFy, appearance,odor and properties vary with specific compounds.


Any inorganic salt of hydrofluoric acid in which fluorine has a valence of 1. Fluorides are major environmental pollutants released into the atmosphere from aluminum reduction, steel manufacturing, and coal-fired power plants. Fluoride pollution is assoc


Fluorides are used as an electrolyte in aluminum manufacture; a flux in smelting nickel, copper, gold, and silver; as a catalyst for organic reactions, a wood preservative; fluoridation agent for drinking water; a bleaching agent for cane seats; in pesticides, rodenticides, and as a fermentation inhibitor. They are utilized in the manufacture of steel, iron, glass, ceramics, pottery, enam els, in the coagulation of latex; in coatings for welding rods; and in cleaning graphite, metals, windows, and glass ware. Exposure to fluorides may also occur during prepara tion of fertilizer from phosphate rock by addition of sulfuric acid. Air pollution by fluoride dusts and gases has done substantial damage to vegetation and to animals in the vicinity of industrial fluoride sources. However, the contri bution of ambient air to human fluoride intake is only a few hundredths of a milligram per day, an amount that is insignificant in comparison with other sources of fluoride. Operations that introduce fluoride dusts and gases into the atmosphere include: Grinding, drying, and calcining of fluoride-containing minerals; acidulation of the minerals; smelting; electrochemical reduction of metals with fluoride fluxes or melts, as in the aluminum and steel industry; kiln firing of brick and other clay products and the combustion of coal.

FLUORIDE STANDARD Basic Attributes

19

18.998403162

Q80VPU408O

DTXSID9049617

C28149

2826 19 10

Characteristics

1.000 g/cm3 (20 °C)

135℃

1.3358 (589.3 nm 20℃)

Immiscible with water.

human,LDLo,oral,50mg/kg (50mg/kg),LUNGS, THORAX, OR RESPIRATION: OTHER CHANGESKIDNEY, URETER, AND BLADDER: OTHER CHANGES LIVER: OTHER CHANGES,IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 27, Pg. 237, 1982.

6 (H2O, 20°C)

2-8°C

Safety Information

NWG not water endangering

Storage color will depend on compound. Prior toworking with fluorides you should be trained on its properhandling and storage. Fluorides must be stored to avoidcontact with strong acids (i.e., hydrochloric, sulfuric, andnitric) since violent reactions can occur. Fluorides formexplosive gases on contact with nitric acid. Store in tightlyclosed containers in a cool, well-ventilated area away fromwater.

Highly toxic; poison; mutagen; can cause convulsions, changes in the respiratory system, liver and kidneys.

Fluorides form explosive gases on con tact with strong acids or acid fumes.

Toxicity

ACGIH: TWA 2.5 mg/m3NIOSH: IDLH 250 mg/m3; TWA 2.5 mg/m3

Drug Information

Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed) (See all compounds classified as Cariostatic Agents.)

Small amounts of fluoride appear to be an essential nutrient. People in the United States ingest about 2 mg/day in water and food. A concentration of about 1 mg/L in drinking water effectively reduces dental caries without harmful effects on health. Dental fluorosis can result from exposure to concentrations above 2 mg/L in children up to about 8 years of age. In its mild form, fluorosis is characterized by white opaque mottled areas on tooth surfaces. Severe fluorosis causes brown to black stains and pitting. Although the matter is controversial, the EPA has determined that dental fluorosis is a cosmetic and not a toxic or an adverse health effect. Water hardness limits fluoride toxicity to humans and fish. The severity of fluorosis decreases in harder drinking water. Crippling skeletal fluorosis in adults requires the consumption of about 20 mg or more of fluoride per day over a 20-year period. No cases of crippling skeletal fluorosis have been observed in the United States from the longterm consumption of 2 L/day of water containing 4 mg/L of fluoride. The EPA has concluded that 0.12 mg/kg/day of fluoride is protective of crippling skeletal fluorosis. Fluoride therapy, where 20 mg/day is ingested for medical purposes, is sometimes used to strengthen bone, particularly spinal bones.

Fluoride

FLUORIDE STANDARD Use and Manufacturing

Fluoride, Ion chromatography standard solution, Specpure|r, F|- 1000μg/ml is used as a standard solution in analytical chemistry and in ion chromatography. It is used for calibration of ion chromatography and other analytical techniques.

Drug Function and Efficacy

Provides anticariogenic effects through remineralization of tooth enamel and reduction of acid production by oral bacteria.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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