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Home > Encyclopedia > N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine structure

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine 

structure
  • CAS No:

    159857-60-0

  • Formula:

    C41H40N2O5

  • Chemical Name:

    N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine

  • Synonyms:

    (S)-2-(((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)carbonylamino)-6-((4-methoxyphenyl)diphenylmethylamino)hexanoic acid;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-[(4-methoxyphenyl)diphenylmethyl]-L-lysine;N6-(4-Methoxytrityl)-L-lysine, N2-FMOC protected;N6-[Diphenyl(4-methoxyphenyl)methyl]-N2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-lysine, FMOC-L-LYS(MMT)-OH;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexanoic acid;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexan;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)he;Nα-Fmoc-Nε-4-methoxyyltrityl-L-lysine≥ 99.8% (HPLC, Chiral purity)

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

White to pale brown solid


An excellent derivative for the synthesis of branched peptides and peptides modified at the lysine side-chain [1], and for the construction of templates and multifunctionalized resins for combinatorial synthesis.The side-chain Mmt group can be selectively removed in the same manner as Mtt with 1% TFA in DCM [2, 3, 4] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [5]. Alternatively, it can be removed under milder conditions with AcOH/TFE/DCM (1:2:7) [1], leaving Mtt intact.The product number for this product was previously 04-12-1232.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine Basic Attributes

640.77

640.29372238

DTXSID40465311

off-white

2924297099

Characteristics

1.210

814.1±65.0 °C(Predicted)

3.83±0.21(Predicted)

Store at +2°C to +8°C.

Safety Information

WGK 3

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine Use and Manufacturing

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine is used in peptide synthesis.

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