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4-Pyridineethanol

4-Pyridineethanol structure

CAS No:
5344-27-4
Formula:
C7H9NO
Chemical Name:
4-Pyridineethanol
Synonyms:
4-Pyridineethanol;4-(2-Hydroxyethyl)pyridine;4-(β-Hydroxyethyl)pyridine;2-(4-Pyridyl)ethanol;2-(γ-Pyridyl)ethanol;2-(4-Pyridyl)-1-ethanol;NSC 1096;2-(4-Pyridinyl)ethanol;2-(Pyridin-4-yl)ethan-1-ol
Categories:
Chemical Reagents > Organic Reagents

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Description

Liquid

4-Pyridineethanol Basic Attributes

Molecular Weight：

123.155

Exact Mass：

123.15

EC Number：

226-286-9

UNII：

I89RDQ5YD9

NSC Number：

1096

DSSTox ID：

DTXSID4044953

HScode：

2933399090

Characteristics

PSA：

33.1

XLogP3：

0.1

Appearance：

Liquid

Density：

1.5±0.1 g/cm3

Melting Point：

13.1-13.3 °C

Boiling Point：

146-147 °C @ Press: 8 Torr

Flash Point：

192.3±27.9 °C

Refractive Index：

1.616

Water Solubility：

Miscible with water.

Safety Information

hazard class code：

R36/37/38

safety instructions：

S26-S36

RTECS Number：

UT2971000

Marks：

Precautionary statement(s)：

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 5 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

4-Pyridineethanol Use and Manufacturing

Methods of Manufacturing

General procedure: Phenethyl alcohol (3a) A two neck Schlenk flask equipped with a magnetic stirring bar and septum was heated with heat gun (~400 °C) for 10 min under high vacuum. After cooling to room temperature, the flask was flushed with argon (3 times). Zn-dust (654 mg, 2.0 equiv, 10.0 mmol) was added followed by THF (20 mL). 1, 2-Dibromoethane (5 molpercent) was added and the reaction mixture was heated until ebullition occurs. After cooling to rt, chlorotrimethylsilane (1 molpercent) was added and the mixture was heated again till ebullition occurs. The flask was again cooled to rt and benzyl chloride (633 mg, 5.0 mmol, 1 equiv) was added as a solution in THF (10 mL) and it was heated at 70 °C for 2 h and cooled to rt. Paraformaldehyde (450 mg, 3.0 equiv. 15.0 mmol) was slowly added at rt and the flask was again heated at 70 °C for 6 h. The solution was cooled to rt and saturated NH

Uses

Intermediates

Manufacturing Info：

All other basic organic chemical manufacturing|4-Pyridineethanol: ACTIVE

Computed Properties

Molecular Weight:123.15
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:123.068413911
Monoisotopic Mass:123.068413911
Topological Polar Surface Area:33.1
Heavy Atom Count:9
Complexity:69.3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 4-Pyridineethanol

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

4-Pyridineethanol

CAS No.: 5344-27-4

Content: 99.00%

Inquiry
Hangzhou KieRay Chem Co.,LTD Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of fine chemicals,pharmaceutical materials

4-Pyridineethanol

CAS No.: 5344-27-4

Grade: industrial Grade

Content: 98%

Inquiry
Compound Net Biotechnology Inc. Contact Supplier

CN
2 YRS

Business licensed Certified factory

Manufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acid

5344-27-4 2-pyridin-4-ylethanol

CAS No.: 5344-27-4

Grade: Industrial Grade

Content: 95%

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