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Benzonal

Benzonal structure

Benzonal 

structure
  • CAS No:

    744-80-9

  • Formula:

    C19H16N2O4

  • Chemical Name:

    Benzonal

  • Synonyms:

    2,4,6(1H,3H,5H)-Pyrimidinetrione,1-benzoyl-5-ethyl-5-phenyl-;Barbituric acid,1-benzoyl-5-ethyl-5-phenyl-;1-Benzoyl-5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione;Benzonal;1-Benzoyl-5-phenyl-5-ethylbarbituric acid;1-Benzoyl-5-ethyl-5-phenylbarbituric acid;Benzobarbital;Benzoylluminal;1-Benzoyl-5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione;113960-20-6

Benzonal Basic Attributes

336.34

336.34

1592732-453-0

DTXSID1046138

2933540000

Characteristics

83.6

2.25

1.3±0.1 g/cm3

134-135 °C

472.83°C (rough estimate)

1.600

Oral-Mouse LD50: 982 mg/kg

Flammable; burning produces toxic nitrogen oxide fumes

Safety Information

III

6.1(b)

3249

Ventilated, low temperature and dry

Toxicity

moderately toxic

Drug Information

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)|Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)|Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other purposes, e.g. military. (See all compounds classified as Radiation-Protective Agents.)|Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)

benzobarbital

Benzonal Use and Manufacturing

Antiepileptic drugs

Computed Properties

Molecular Weight:336.3
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:336.11100700
Monoisotopic Mass:336.11100700
Topological Polar Surface Area:83.6
Heavy Atom Count:25
Complexity:576
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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