Digitalin

Digitalin is a cardenolide glycoside. It derives from a gitoxigenin.|Digitalin is a glycoside compound, extracted from the leaves and seeds of the common foxglove, with anti-arrhythmic property. Digitalin inhibits the enzymatic activity of the sodium-potassium ATPase pump in cardiac tissue, thereby increasing intracellular sodium and calcium levels and providing a positive inotropic effect. This results in increased force of myocardial muscle contraction. This agent also has a vagal effect on the parasympathetic nervous system, and as such slows the ventricular heart rate as well as helps eliminate fluid from body tissues.

Molecular Weight:712.8
XLogP3:-0.3
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:14
Rotatable Bond Count:7
Exact Mass:712.36700646
Monoisotopic Mass:712.36700646
Topological Polar Surface Area:214
Heavy Atom Count:50
Complexity:1300
Defined Atom Stereocenter Count:19
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes