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Home > Encyclopedia > 10-Hydroxy-2-decenoic acid

10-Hydroxy-2-decenoic acid

10-Hydroxy-2-decenoic acid structure

10-Hydroxy-2-decenoic acid 

structure
  • CAS No:

    765-01-5

  • Formula:

    C10H18O3

  • Chemical Name:

    10-Hydroxy-2-decenoic acid

  • Synonyms:

    2-Decenoic acid,10-hydroxy-;10-Hydroxy-2-decenoic acid;10-Hydroxy-Δ2-decenoic acid

  • Categories:

    Cosmetic Ingredient  >  Skin Conditioning

10-Hydroxy-2-decenoic acid Basic Attributes

186.25

186.25

1592732-453-0

2932999099

Characteristics

57.5

2.2

1.0±0.1 g/cm3

55 °C

338.7°C at 760 mmHg

173.1±16.9 °C

1.486

Safety Information

P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362

H315

Drug Information

10-HDEC

10-Hydroxy-2-decenoic acid Use and Manufacturing

4. Saponification Reaction0.60 g (2.81 mmol) of hydroxyester obtained in the preceding step are solubilized in 10 volumes of tetrahydrofurane. 3.4 ml (6.75 mmol) of a 2M soda solution are slowly added. The medium is heated to 65° C. for 3 hours. Once the reaction is completed, the medium is hydrolyzed by adding a 3M hydrochloric acid solution, until pH=2 is obtained. The mixture is dry-concentrated and the aqueous phase is then extracted with ethyl acetate. The organic phases are washed with a NaCl saturated solution, dried on MgSO4. Saponification Reaction0.60 g (2.81 mmol) of hydroxyester obtained in the preceding step are solubilized in 10 volumes of tetrahydrofurane. 3.4 ml (6.75 mmol) of a 2M soda solution are slowly added. The medium is heated to 65° C. for 3 hours. Once the reaction is completed, the medium is hydrolyzed by adding a 3M hydrochloric acid solution, until pH=2 is obtained. The mixture is dry-concentrated and the aqueous phase is then extracted with ethyl acetate. The organic phases are washed with a NaCl saturated solution, dried on MgSO

Computed Properties

Molecular Weight:186.25
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:186.125594432
Monoisotopic Mass:186.125594432
Topological Polar Surface Area:57.5
Heavy Atom Count:13
Complexity:152
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

It is a major active component in royal jelly, known for its biological activities including immune modulation, antibacterial properties, and potential role in enhancing sleep quality. It is also a key indicator for assessing the quality of royal jelly.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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