10-Hydroxy-2-decenoic acid
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10-Hydroxy-2-decenoic acid
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CAS No:
765-01-5
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Formula:
C10H18O3
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Chemical Name:
10-Hydroxy-2-decenoic acid
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Synonyms:
2-Decenoic acid,10-hydroxy-;10-Hydroxy-2-decenoic acid;10-Hydroxy-Δ2-decenoic acid
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CAS No:
10-Hydroxy-2-decenoic acid Use and Manufacturing
4. Saponification Reaction0.60 g (2.81 mmol) of hydroxyester obtained in the preceding step are solubilized in 10 volumes of tetrahydrofurane. 3.4 ml (6.75 mmol) of a 2M soda solution are slowly added. The medium is heated to 65° C. for 3 hours. Once the reaction is completed, the medium is hydrolyzed by adding a 3M hydrochloric acid solution, until pH=2 is obtained. The mixture is dry-concentrated and the aqueous phase is then extracted with ethyl acetate. The organic phases are washed with a NaCl saturated solution, dried on MgSO4. Saponification Reaction0.60 g (2.81 mmol) of hydroxyester obtained in the preceding step are solubilized in 10 volumes of tetrahydrofurane. 3.4 ml (6.75 mmol) of a 2M soda solution are slowly added. The medium is heated to 65° C. for 3 hours. Once the reaction is completed, the medium is hydrolyzed by adding a 3M hydrochloric acid solution, until pH=2 is obtained. The mixture is dry-concentrated and the aqueous phase is then extracted with ethyl acetate. The organic phases are washed with a NaCl saturated solution, dried on MgSO
Computed Properties
Molecular Weight:186.25
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:186.125594432
Monoisotopic Mass:186.125594432
Topological Polar Surface Area:57.5
Heavy Atom Count:13
Complexity:152
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
It is a major active component in royal jelly, known for its biological activities including immune modulation, antibacterial properties, and potential role in enhancing sleep quality. It is also a key indicator for assessing the quality of royal jelly.
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