N-Bromoacetamide
-
N-Bromoacetamide
structure -
-
CAS No:
79-15-2
-
Formula:
C2H4BrNO
-
Chemical Name:
N-Bromoacetamide
-
Synonyms:
Acetamide,N-bromo-;N-Bromoacetamide;Acetobromamide;NBA
-
CAS No:
Description
PHYSICAL DESCRIPTION: White powder. (NTP, 1992)
N-bromoacetamide is a white powder. (NTP, 1992)
N-bromoacetamide is a white powder. (NTP, 1992)
N-Bromoacetamide Basic Attributes
137.96
137.96
969346
201-181-0
0AQ6MWH7ZB
3261
DTXSID5024633
2924199090
Characteristics
29.1
0.82330
white to yellow powder
1.71 g/cm3
103.5 °C
127-130 °C @ Press: 16 Torr
1.474
soluble in water.
−20°C
Soluble in water.
Amides and Imides
N-BROMOACETAMIDE is sensitive to light, moisture, and heat. (NTP, 1992). It decomposes rapidly at elevated temperatures, in the presence of moisture and light.
Safety Information
III
8
3261
3
36/37/38
26-36
Xi
P261-P305 + P351 + P338
H315-H319-H335
Flash point data are not available for this chemical, but it is probably combustible. (NTP, 1992)
|Danger|H314 (11.11%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P261, P264, P271, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 45 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Fires involving this compound should be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should protect this chemical from exposure to light, and store it in a freezer. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Drug Information
Agents destructive to snails and other mollusks. (See all compounds classified as Molluscacides.)
SYMPTOMS: This compound may cause irritation of tissues on contact. Related compounds such as bromoacetate are highly toxic and may cause fatal cardiac arrhythmias and delayed seizures. ACUTE/CHRONIC HAZARDS: This compound is an irritant. When heated it emits toxic fumes. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
N-bromoacetamide
N-Bromoacetamide Use and Manufacturing
Derived from the reaction of acetamide and bromine. Dissolve acetamide in molar liquid bromine, after cooling to 4-5°C, add pre-cooled potassium hydroxide solution with stirring. The resulting semi-solid is placed at 0-5°C for 2-3h. Sodium chloride and chloroform were added to the reaction mixture, and after stirring and heating, the chloroform solution was poured out from the solid substance, and the mixture was extracted twice with chloroform. The extract was dried with anhydrous sodium sulfate and filtered. Add ethane to precipitate crystals, cool, filter, wash with hexane, and dry to obtain N-bromoacetamide. The yield is about 50%.
Used in organic synthesis. As a brominating agent, oxidant, catalyst.
Acetamide, N-bromo-: ACTIVE
Computed Properties
Molecular Weight:137.96
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:136.94763
Monoisotopic Mass:136.94763
Topological Polar Surface Area:29.1
Heavy Atom Count:5
Complexity:44.9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of N-Bromoacetamide
-
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives
- Hot Searches
- pinacol
- iodic acid
- sodium hypobromite
- echemi
- water sds
- n2o3 name