METHYLALPHA-BROMOPHENYLACETATE

General procedure: 2'-Methyl phenyl benzoate (2a) (3.18 g, 15 mmol) and N-bromosuccinimide (2.67 g, 15 mmol) were taken in dry CCl60.07 g of [2-(bromoethyl)phenyl] acetate, 400 mmol of 2-methylphenylacetic acid, 106.8 g of N-bromosuccinimide and 500 ml of cyclohexane were added to a 1 L flask and added with vigorous stirring3.284 g of azobisisobutyronitrile and stir for 30 minutes, Mixing was stirred at 80C until no further conversion was observed. Work-up after reaction: then cooled to room temperature, the precipitate was removed by filtration and the filtrate was washed with cyclohexane to give compound S6-5 in 90percent yield.Starting compound 64a (225 mg, 0.262 mmol) and anhydrous potassium carbonate (256 mg, 1.85 mmol) were placed into a 50 mF flask under argon atmosphere and anhydrous acetonitrile (20 mF) was added.

Molecular Weight:229.07
XLogP3:2.5
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:227.97859
Monoisotopic Mass:227.97859
Topological Polar Surface Area:26.3
Heavy Atom Count:12
Complexity:159
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes