(3,4-Dimethoxyphenyl)acetone

CLEAR YELLOW TO BROWN LIQUID

General procedure: To the solution of olefine (1 mmol), in THF/water (4:1, 15 mL), 10percent Pd/C (0.05 mmol) and KBrO(0.2 mol, 95percent) of 1, 2-dimethoxy-4- (2-methylallyl) benzene was added to a 250 mL four-necked flask, (0.6 mol) of O' (Oxygen source, O' Content of about 6.2percent) was cooled to -5 ° C, (0.2mol) Zn powder was added in 5 batches. The temperature of the reaction solution was controlled at about -5 , stirred for 3 hours and filtered. The reaction was carried out at room temperature for 1 hour, 50 mL of ethyl acetate, washed with water and dried over anhydrous sodium sulfate. After the organic phase was dissolved, the vacuum distillation was carried out using a ceramic packed-tower packed column (refluxing ratio of 5: 1) and a boiling range of 122-124 ° C / 5 mmHg, To give 33.4 g of a pale yellow oily liquid of veratrylacetone in an amount of 99.0percent in a yield of 85.0percent.

Molecular Weight:194.23
XLogP3:1.1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:194.094294304
Monoisotopic Mass:194.094294304
Topological Polar Surface Area:35.5
Heavy Atom Count:14
Complexity:191
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes