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Home > Encyclopedia > 2′,3′-Didehydro-2′,3′-dideoxyadenosine

2′,3′-Didehydro-2′,3′-dideoxyadenosine

2′,3′-Didehydro-2′,3′-dideoxyadenosine structure

2′,3′-Didehydro-2′,3′-dideoxyadenosine 

structure
  • CAS No:

    7057-48-9

  • Formula:

    C10H11N5O2

  • Chemical Name:

    2′,3′-Didehydro-2′,3′-dideoxyadenosine

  • Synonyms:

    Adenosine,2′,3′-didehydro-2′,3′-dideoxy-;Adenine,9-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)-;2′,3′-Didehydro-2′,3′-dideoxyadenosine;2′,3′-Dideoxy-2′,3′-didehydroadenosine;Pent-2-enofuranoside,adenine-9 2,3-dideoxy-;NSC 108602;14585-76-3;16546-25-1

  • Categories:

    Biochemical Engineering  >  Saccharides

Description

NSC 108602 is a nucleoside HIV-1 reverse transcriptase inhibitor.

2′,3′-Didehydro-2′,3′-dideoxyadenosine Basic Attributes

233.231

233.23

108602

Characteristics

99.1

-0.4

1.74 g/cm3

191-192 °C

553.9ºC at 760 mmHg

288.8ºC

1.822

Drug Information

Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template. (See all compounds classified as Reverse Transcriptase Inhibitors.)|Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)|Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS. (See all compounds classified as Anti-HIV Agents.)

2'3'-DDDA

Computed Properties

Molecular Weight:233.23
XLogP3:-0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:233.09127461
Monoisotopic Mass:233.09127461
Topological Polar Surface Area:99.1
Heavy Atom Count:17
Complexity:313
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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