 Home > Encyclopedia > Erythrityl tetranitrate

Erythrityl tetranitrate

Erythrityl tetranitrate structure

CAS No:
7297-25-8
Formula:
C4H6N4O12
Chemical Name:
Erythrityl tetranitrate
Synonyms:
1,2,3,4-Butanetetrol,1,2,3,4-tetranitrate,(2R,3S)-rel-;Erythritol,tetranitrate;1,2,3,4-Butanetetrol,tetranitrate,(R*,S*)-;1,2,3,4-Butanetetrol,tetranitrate,(2R,3S)-rel-;Cardilate;Nitroerythrite;Tetranitrin;Tetranitrol;ETN;Erythrol tetranitrate;Erythrityl tetranitrate;meso-Erythritol tetranitrate;1,2,3,4-Butanetetrayl tetranitrate;Cardiloid;Cardivell;Nitroerythrol;Eritrityl tetranitrate;NSC 106566
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Description

Crystals. Soluble in alcohol, ether, and glycerol; insoluble in water.

A vasodilator with general properties similar to NITROGLYCERIN. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1020)

Erythrityl tetranitrate Basic Attributes

Molecular Weight：

302.11000

Exact Mass：

302.11

EC Number：

230-734-9

NSC Number：

106566

DSSTox ID：

DTXSID9022990

Characteristics

PSA：

220.20000

XLogP3：

0.64960

Appearance：

Solid

Density：

1.757 g/cm3

Melting Point：

61 °C

Boiling Point：

381.8ºC at 760 mmHg

Flash Point：

178.8ºC

Refractive Index：

1.511

Water Solubility：

1.95e-01 g/L

Drug Information

MeSH：

Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

MeSH Entry Terms：

Cardilate

Erythrityl tetranitrate Use and Manufacturing

Vasodilator (coronary). Cardilate (Glaxo Wellcome{) [Name previously used: Erythrol Tetranitrate.].

Computed Properties

Molecular Weight:302.11
XLogP3:1.4
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:7
Exact Mass:301.99822164
Monoisotopic Mass:301.99822164
Topological Polar Surface Area:220
Heavy Atom Count:20
Complexity:326
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes