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Sodium nafcillin monohydrate

Sodium nafcillin monohydrate structure

CAS No:
7177-50-6
Formula:
C21H22N2O5S.H2O.Na
Chemical Name:
Sodium nafcillin monohydrate
Synonyms:
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-,sodium salt,hydrate (1:1:1),(2S,5R,6R)-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-,monosodium salt,monohydrate;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt,monohydrate,[2S-(2α,5α,6β)]-;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-,monosodium salt,monohydrate,(2S,5R,6R)-;Sodium nafcillin monohydrate;Sodium 6-(2-ethoxy-1-naphthamido)penicillanate monohydrate;Nafcillin sodium hydrate;219581-32-5
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Nafcillin sodium monohydrate is a semi-synthetic antibiotic related to penicillin.Target: AntibacterialNafcillin sodium is a narrow-spectrum, beta-lactam antibiotic of the penicillin class. As a beta-lactamase-resistant penicillin, it is used to treat infections caused by Gram-positive bacteria, in particular, species of staphylococci that are resistant to other penicillins. Nafcillin is considered therapeutically equivalent to oxacillin, although its safety profile is somewhat different

Sodium nafcillin monohydrate Basic Attributes

Molecular Weight：

454.47

Exact Mass：

454.117462

EC Number：

1308068-626-2

HScode：

29411099

Characteristics

PSA：

121

XLogP3：

3.3

Appearance：

Solid

Density：

1.42 g/cm3

Boiling Point：

714.1°C at 760 mmHg

Flash Point：

385.7ºC

Water Solubility：

H2O: soluble 50mg/mL

Storage Conditions：

2-8°C

Safety Information

Packing level：

Ⅲ

Transport codes：

2811

wgk germany：

hazard class code：

36/37/38-42/43

safety instructions：

26-36-24/25

Marks：

Stability/Shelf Life：

STABLE @ ROOM TEMP FOR 2-4 YR /DRY STATE/ DEPENDING ON DOSAGE FORM

Precautionary statement(s)：

P261-P280-P284-P304 + P340-P305 + P351 + P338-P342 + P311

Hazard Statements：

H315-H317-H319-H334-H335

Sodium nafcillin monohydrate Use and Manufacturing

An antibiotic resistant to beta-lactamase.

Drug Function and Efficacy

Not yet clear

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Nafcillin Sodium Capsules
Ingredients	The main ingredient is nafcillin sodium.
Indication	1. This product is incompatible with aminoglycosides, norepinephrine, metaraminol, phenobarbital, vitamin B group, vitamin C and other drugs, and should not be dripped in the same bottle. 2. Probenecid can reduce the renal tubular secretion of ethotripsy penicillin and prolong the serum half-life of this product. 3. Aspirin and sulfonamides reduce the absorption of this product in the gastrointestinal tract, and can inhibit the binding of this product to serum proteins, increasing the free blood concentration of this product.
Specifications	0.25g (calculated as C21H22N2O5S)

Nafcillin Sodium

Nafcillin sodium (for oral use)

See More Related Drugs

Registered Holders

CSPC Zhongnuo PHARMACEUTICAL(Shijiazhuang) Co., Ltd.

China
Active
Shanxi Taiyue Pharmaceutical Co., Ltd.

China
Active
LATINA PHARMA SPA

United States
Inactive

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Recommended Suppliers of Sodium nafcillin monohydrate

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5 YRS

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Nafcillin sodium salt monohydrate

CAS No.: 7177-50-6

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Guide of Sodium nafcillin monohydrate

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
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