2-NITRO-3-ACETYLAMINO-4-METHYLBENZOICACID

To a solution of HN0Example 42 Preparation of 3-acetamido-4-methyl-2-nitrobenzoic acid3-Acetamido-4-methylbenzoic acid (205 g, 1061 mmol) was added portionwise over 45 min to stirred fuming nitric acid (1 L) at -5 To a solution of fuming HN03-(acetylamino)-4-methylbenzoic acid (300 g, 1.55 mol) was added portionwise to fuming nitric acid (1200 mL) with stirring over a period of 1 h at 0~5°C. The solution gradually turned into a heavy slurry during the addition. At the end of addition, an additional fuming nitric acid (200 mL) was added. The reaction mixture was stirred for an additional hour at 5Preparation of 3-(Acetylamino)-4-methyl-2-nitrobenzoic Acid (15):

Molecular Weight:238.20
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:238.05897142
Monoisotopic Mass:238.05897142
Topological Polar Surface Area:112
Heavy Atom Count:17
Complexity:338
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes