Sodium iodate

197.89

197.878967

231-672-5

U558PCS5Z9

DTXSID90858754

White, crystal powder|White rhombic crystals

28299000

57.20000

0.52930

White Powder/Solid

4.28 g/cm³

decomposes [STR93]

H2O: soluble

Store at +5°C to +30°C.

LD50 in female mice (mg/kg): 119 ±4 i.p., 108 ±4 i.v., 505 ±26 orally (Webster)

MIXTURES OF SODIUM WITH SILVER OR SODIUM IODATES EXPLODE WHEN INITIATED BY SHOCK.

Aq soln is neutral

Two hydrates exist in saturated solution, the pentahydrate up to 19.85 °C and the monohydrate from 19.85-73.4 °C.

Neutral in solution

II

5.1

UN 1479 5.1/PG 2

3

8-22-42/43-36/37/38

17-22-36/37-45-37/39-26

NN1400000

O,Xn

Stable. Strong oxidizer. Incompatible with finely powdered metals, arsenic, carbon, phosphorus, sulphur, metal cyanides, thiocyanates, impure manganese dioxide, sulphuric acid. May decompose on exposure to light, air or moisture. Heat and shock sensitive.

P220-P261-P280-P342 + P311

H272-H302-H317-H334

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

May react violently with aluminum; arsenic; carbon; copper; hydrogen peroxide; metal sulfides; organic matter; phosphorus; potassium; sulfur.

|Danger|H272 (91.55%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]|P210, P220, P221, P261, P264, P270, P272, P280, P285, P301+P312, P302+P352, P304+P341, P321, P330, P333+P313, P342+P311, P363, P370+P378, and P501|Aggregated GHS information provided by 71 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Warning|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P260, P264, P270, P301+P312, P309+P311, P330, P405, and P501|H272: May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]|P210, P220, P221, P264, P270, P273, P280, P301+P312, P330, P370+P378, and P501

SEE IODATES. THESE MATERIALS ARE A MODERATE FIRE HAZARD BECAUSE THEY ARE POWERFUL OXIDIZERS. IN CONTACT WITH FLAMMABLE OR EVEN COMBUSTIBLE MATERIALS THEY CAN START FIRES. /IODATES/

...OXYGEN-CONTAINING SUBSTANCES WHICH REACT VIOLENTLY OR EXPLOSIVELY INCLUDE SODIUM...IODATES...|MIXTURES OF SODIUM WITH SILVER OR SODIUM IODATES EXPLODE WHEN INITIATED BY SHOCK.

ALTHOUGH OTHER OXIDIZING AGENTS HAVE NOT GENERALLY PROVED RETINOTOXIC, IT HAS BEEN SHOWN THAT INJURIOUS EFFECT OF IODATE IN EYE IS POTENTIZED BY OXIDIZING AGENT POTASSIUM PERMANGANATE, AND ANTAGONIZED BY REDUCING AGENT CYSTEINE, BUT NOT BY ADMINISTERING ASCORBIC ACID. /IODATE/

LD50 Mouse ip 119 mg/kg|LD50 Mouse iv 108 mg/kg

4. 4= VERY TOXIC: PROBABLE ORAL LETHAL DOSE FOR HUMANS IS 50-500 MG/KG; BETWEEN 1 TEASPOON AND 1 OUNCE FOR 70 KG PERSON (150 LB).

WHEN IODATE (131)I HAS BEEN GIVEN INTRAVENOUSLY, LABELED IODINE HAS BEEN FOUND TO PASS RAPIDLY INTO AQUEOUS & VITREOUS HUMORS IN RABBITS. THAT REMAINING IN BLOOD PERSISTS FOR MANY HOURS & IS GRADUALLY REDUCED BY THE LIVER TO IODIDE. /IODATE/|WITHIN FEW MIN AFTER SINGLE IV DOSE THERE WAS MARKED INCR IN RATE OF PENETRATION OF SODIUM, IODINE & THIOUREA INTO VITREOUS BODY OF RABBIT, MAX EFFECT REACHED WITHIN 30-60 MIN. PATTERN OF ALTERED PERMEABILITY OF BLOOD-VITREAL BARRIER CONFIRMED IDEA OF EXCLUSIVE ATTACK ON CILIARY BODY.|EXPT RETINAL DEGENERATION INDUCED IN RABBITS BY DAILY INJECTIONS OF 30 MG/KG. IN 2-24 HR INTENSE FLUORESCEIN COLORATION APPEARED IN OUTER PART OF RETINA. IN 1-3 WK FLUORESCEIN PASSAGE INTO RETINA GRADUALLY DECR ALTHOUGH THE ALMOST VISUAL CELLS HAD DISAPPEARED.|ACCUM OF IODATE IN EYE TISSUES & FLUIDS AS POSSIBLE EXPLANATION OF RETINOTOXIC EFFECT OF IODATE WAS STUDIED BY IV INJECTION OF NAIO3 (30 MG/KG). EFFECT OF IODATE IS NOT DUE TO ACCUM OF IO3 IN EYE TISSUE, BUT TO DAMAGE TO BIOCHEM MECHANISMS INVOLVED IN REDN TO I-.

...PT...GIVEN SEPTOJOD IV OR IP...HAD MARKED REDUCTION OF VISION WITHIN 24 HR. ...DEVELOPED DISTURBANCE OF RETINAL PIGMENT EPITHELIUM... IN MOST PT VISION EVENTUALLY IMPROVED...BUT IN MAJORITY CENTRAL SCOTOMA...OR CONSTRICTION OF VISUAL FIELDS PERSISTED... IODATE IN /SEPTOJOD/...RESPONSIBLE FOR OCULAR INJURIES. /IODATE/

NaIO3

The article of commerce contains about 99% NaIO3.|Grades: CP, reagent, technical

Iodic acid (HIO3), sodium salt (1:1): ACTIVE

....determined by addition of excess alkali iodide in an acid solution followed by titration of the liberated iodine with thiosulfate.

Cosmetics -> Preservative