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Iprindole

Iprindole structure

Iprindole 

structure
  • CAS No:

    5560-72-5

  • Formula:

    C19H28N2

  • Chemical Name:

    Iprindole

  • Synonyms:

    5H-Cyclooct[b]indole-5-propanamine,6,7,8,9,10,11-hexahydro-N,N-dimethyl-;5H-Cyclooct[b]indole,5-[3-(dimethylamino)propyl]-6,7,8,9,10,11-hexahydro-;6,7,8,9,10,11-Hexahydro-N,N-dimethyl-5H-cyclooct[b]indole-5-propanamine;5-[3-(Dimethylamino)propyl]-6,7,8,9,10,11-hexahydro-5H-cyclooct[b]indole;Iprindole;Pramindole;Tertran;NSC 169449

Description

Iprindole is a member of indoles.|A tricyclic antidepressant that has actions and uses similar to those of AMITRIPTYLINE, but has only weak antimuscarinic and sedative effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p257)

Iprindole Basic Attributes

284.447

284.44

226-933-5

69U0IKR8FP

169449

DTXSID80204145

N - Nervous system

Characteristics

8.2

4.25200

1.04g/cm3

146-147 °C

435.4ºC at 760mmHg

217.1ºC

1.573

Drug Information

Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. (See all compounds classified as Antidepressive Agents, Tricyclic.)

Iprindole

Iprindole Use and Manufacturing

Uses

Antidepressant.

Pharmaceuticals

Computed Properties

Molecular Weight:284.4
XLogP3:4.6
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:284.225248902
Monoisotopic Mass:284.225248902
Topological Polar Surface Area:8.2
Heavy Atom Count:21
Complexity:315
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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