4-Pentenoic acid, 3,3-dimethyl-, ethyl ester

The preparation method is to put 3-methylbutene[2] alcohol and triethyl orthoacetate into the reaction pot, add phenol as a catalyst, stir and gradually heat to 140°C, stir while heating, and distill out ethanol. The reaction is approximately 20h, until the ethanol is evaporated, the reaction is over, move to the distillation pot for vacuum distillation, first remove the triethyl orthoacetate, and then collect the 74～78℃/7.33kPa fraction, which is 3, 3-dimethylpentene [4 ] Ethyl acid, the yield is about 75%. In this reaction, triethyl orthoacetate should be excessive to avoid the formation of isopentenyl pentene acid. In addition to phenol, phosphoric acid, isobutyric acid and hydroquinone can also be used as the catalyst.

Ethyl bentonate, ethyl 3,3-dimethylpentene[4] acid, is an important intermediate for pyrethroids, and can synthesize ethyl permethrin and trifluthrin.

Molecular Weight:156.22
XLogP3:2.4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:156.115029749
Monoisotopic Mass:156.115029749
Topological Polar Surface Area:26.3
Heavy Atom Count:11
Complexity:148
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes