5-[(2-Chloroethyl)(2-fluoroethyl)amino]-6-methyl-2,4(1H,3H)-pyrimidinedione
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![5-[(2-Chloroethyl)(2-fluoroethyl)amino]-6-methyl-2,4(1H,3H)-pyrimidinedione structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/37e576e4bd554e0d942c46987580213b.png "5-[(2-Chloroethyl)(2-fluoroethyl)amino]-6-methyl-2,4(1H,3H)-pyrimidinedione")
5-[(2-Chloroethyl)(2-fluoroethyl)amino]-6-methyl-2,4(1H,3H)-pyrimidinedione
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CAS No:
834-91-3
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Formula:
C9H13ClFN3O2
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Chemical Name:
5-[(2-Chloroethyl)(2-fluoroethyl)amino]-6-methyl-2,4(1H,3H)-pyrimidinedione
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Synonyms:
2,4(1H,3H)-Pyrimidinedione,5-[(2-chloroethyl)(2-fluoroethyl)amino]-6-methyl-;Uracil,5-[(2-chloroethyl)(2-fluoroethyl)amino]-6-methyl-;5-[(2-Chloroethyl)(2-fluoroethyl)amino]-6-methyl-2,4(1H,3H)-pyrimidinedione;Fluorpan;Fluorodopan;Fluorodopane;NSC 73754;1781-44-8
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CAS No:
Description
Fluorodopan is an alkylating agent with potential antineoplastic activity. Fluorodopan alkylates DNA at the N7 position of guanine. Alkylating agents exert cytotoxic and, in some cases, chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA replication and cell division. (NCI04)
5-[(2-Chloroethyl)(2-fluoroethyl)amino]-6-methyl-2,4(1H,3H)-pyrimidinedione Basic Attributes
249.67
249.67
73754
DTXSID60232320
C29042
Computed Properties
Molecular Weight:249.67
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:249.0680325
Monoisotopic Mass:249.0680325
Topological Polar Surface Area:61.4
Heavy Atom Count:16
Complexity:333
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
5-[(2-Chloroethyl)(2-fluoroethyl)amino]-6-methyl-2,4(1H,3H)-pyrimidinedione
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