2-Aminobenzenesulfonic acid
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2-Aminobenzenesulfonic acid
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CAS No:
88-21-1
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Formula:
C6H7NO3S
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Chemical Name:
2-Aminobenzenesulfonic acid
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Synonyms:
Benzenesulfonic acid,2-amino-;Benzenesulfonic acid,o-amino-;2-Aminobenzenesulfonic acid;Aniline-o-sulfonic acid;Orthanilic acid;o-Sulfanilic acid;2-Anilinesulfonic acid;o-Aminobenzenesulfonic acid;1-Aminobenzene-2-sulfonic acid;o-Aminophenylsulfonic acid;2-Aminophenylsulfonic acid;2-Sulfoaniline;NSC 147;2-Aminobenzene-1-sulfonic acid
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CAS No:
Description
LIGHT BROWN FINE CRYSTALLINE POWDER
2-aminobenzene sulfonic acid is a light brown powder. (NTP, 1992)
2-aminobenzene sulfonic acid is a light brown powder. (NTP, 1992)|2-aminobenzenesulfonic acid is an aminobenzenesulfonic acid carrying an amino group at position 2. It is a conjugate acid of a 2-aminobenzenesulfonate.
2-Aminobenzenesulfonic acid Basic Attributes
173.19000
173.19
201-810-9
ZB9JSA4BH0
147
2585
DTXSID1024463
2921420090
Characteristics
88.77000
0.4
2-aminobenzene sulfonic acid is a light brown powder. (NTP, 1992)
1.512 g/cm3
>320 °C (decomp)
363ºC
1.630
Sparingly soluble with water.
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
153.23 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|133.9 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|130.5 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|131.9 Ų [M-H]-
Soluble in water.
Acids, Weak
2-AMINOBENZENE SULFONIC ACID is an amino acid. Reacts weakly with both acids and bases.
Safety Information
III
8
UN 2585
3
R34
S26-S28
DB4727700
C
Stable under normal temperatures and pressures.
P280-P305 + P351 + P338-P310
H314
Flash point data for this chemical are not available, however it is probably combustible. (NTP, 1992)
|Danger|H314 (58.04%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P337+P313, P363, P405, and P501|Aggregated GHS information provided by 114 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Fires involving this compound can be extinguished using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Drug Information
SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin and mucous membranes. ACUTE/CHRONIC HAZARDS: This compound may evolve toxic fumes on contact with acids or when heated to decomposition. It may be corrosive to tissues. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
2-aminobenzenesulfonate
2-Aminobenzenesulfonic acid Use and Manufacturing
Orthanilic acid (2-aminobenzenesulfonate) is a biological acid with roles in benzoate degradation and microbial metabolism in diverse environments.Orthanilic acid promotes reverse turn formation in peptides, inducing a folded conformation when incorporated into peptide sequences (Xaa-SAnt-Yaa), showing robust 11-membered-ring hydrogen-bonding.Orthanilic acid is a structural component of some azo dyes which consequently have poor bacterial degradation.Oorthanilic acids have also been found to affect cardiac tension.
Benzenesulfonic acid, 2-amino-: ACTIVE
Computed Properties
Molecular Weight:173.19
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:173.01466426
Monoisotopic Mass:173.01466426
Topological Polar Surface Area:88.8
Heavy Atom Count:11
Complexity:219
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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