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Nitrovin

Nitrovin structure

CAS No:
804-36-4
Formula:
C14H12N6O6
Chemical Name:
Nitrovin
Synonyms:
Hydrazinecarboximidamide,2-[3-(5-nitro-2-furanyl)-1-[2-(5-nitro-2-furanyl)ethenyl]-2-propen-1-ylidene]-;Guanidine,[[3-(5-nitro-2-furyl)-1-[2-(5-nitro-2-furyl)vinyl]allylidene]amino]-;Hydrazinecarboximidamide,2-[3-(5-nitro-2-furanyl)-1-[2-(5-nitro-2-furanyl)ethenyl]-2-propenylidene]-;2-[3-(5-Nitro-2-furanyl)-1-[2-(5-nitro-2-furanyl)ethenyl]-2-propen-1-ylidene]hydrazinecarboximidamide;1,4-Pentadien-3-one,1,5-bis(5-nitro-2-furanyl)-,(aminoiminomethyl)hydrazone;Nitrovin;Bis(5-nitro-2-furfurylidene)acetone guanylhydrazone;1,5-Bis(5-nitro-2-furyl)-3-pentadienone amidinohydrazone;Bis(5-nitrofurfurylidine)acetone guanylhydrazone;Difurazone;Biovin 40;2-(1,5-Bis(5-nitrofuran-2-yl)penta-1,4-dien-3-ylidene)hydrazinecarboximidamide
Categories:
Chemical Reagents > Organic Reagents

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Description

An antibacterial growth promoter used in animal feeds.

Nitrovin Basic Attributes

Molecular Weight：

360.28

Exact Mass：

360.28

EC Number：

212-358-7

UNII：

4I203628MT

HScode：

29411099

Characteristics

PSA：

195

XLogP3：

2.58

Density：

1.6±0.1 g/cm3

Melting Point：

217 °C (decomp)

Boiling Point：

550.3±60.0 °C at 760 mmHg

Flash Point：

286.6±32.9 °C

Refractive Index：

1.680

Toxicity：

mmo-sat 2500 ng/L CEHYAN 32,276,87

Safety Information

safety instructions：

24/25

Drug Information

MeSH：

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)

MeSH Entry Terms：

Nitrovin

Nitrovin Use and Manufacturing

Methods of Manufacturing

It is prepared by condensation of 5-nitrofurfural with acetone and aminoguanidine carbonate in the presence of zinc chloride. The yield can reach more than 50%, and the content should be more than 98% according to the regulations of Japan's "Regulations on Pharmaceuticals for Animals".

Uses

Nitrofurene hydrazone is a growth promoter for livestock and poultry, which has the effect of promoting the growth of drought and improving the feed conversion rate. After many years of application in many countries, it has proved to have good results. Feeding with 20ppm of this product will increase weight by 7% and increase feed conversion rate by 5% from the beginning of the pigs to the market. It has no effect on pig health, carcass quality, and meat taste. This product also promotes the growth of lambs and broilers. The oral LD50 of rats is more than 10 g/kg, and that of mice is more than 6.4 g/kg. This product is not absorbed by the gastrointestinal tract and rarely remains in tissues.

Computed Properties

Molecular Weight:360.28
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:360.08183212
Monoisotopic Mass:360.08183212
Topological Polar Surface Area:195
Heavy Atom Count:26
Complexity:601
Undefined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes