ALFENTANILHYDROCHLORIDECII(500MG)
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ALFENTANILHYDROCHLORIDECII(500MG)
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CAS No:
70879-28-6
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Formula:
C21H32N6O3.ClH.H2O
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Chemical Name:
ALFENTANILHYDROCHLORIDECII(500MG)
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Synonyms:
r39209;alfenta;Unii-11S92G0tiw;rapifenhydrochloride;Alfentanil HCl hydrate;Alfentanil hydrochlorid-1-wasser;ALFENTANIL HYDROCHLORIDE MONOHYDRATE;ALFENTANIL HYDROCHLORIDE CII (500 MG);oxymethyl)-4-piperidinyl)-n-phenyl-,hydrochloride,hydrate;propanamide,n-(1-(2-(4-ethyl-4,5-dihydro-5-oxo-1h-tetrazol-1-yl)ethyl)-4-(meth
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CAS No:
Description
Alfenta is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.|Alfentanil Hydrochloride is the hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.|A short-acting opioid anesthetic and analgesic derivative of FENTANYL. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
ALFENTANILHYDROCHLORIDECII(500MG) Basic Attributes
470.999
470.241
11S92G0TIW
9737
DTXSID50221107
C220
2933330000
Characteristics
82
140.8° (Janssens, 1979); mp 138.4° (Janssens, 1986)
LD50 in rats, dogs (mg/kg): 47.5, 20 i.v. (Niemegeers, Janssen)
Drug Information
Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)|Ultrashort-acting anesthetics that are used for induction. Loss of consciousness is rapid and induction is pleasant, but there is no muscle relaxation and reflexes frequently are not reduced adequately. Repeated administration results in accumulation and prolongs the recovery time. Since these agents have little if any analgesic activity, they are seldom used alone except in brief minor procedures. (From AMA Drug Evaluations Annual, 1994, p174) (See all compounds classified as Anesthetics, Intravenous.)|Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. (See all compounds classified as Narcotics.)
Alfenta
Alfentanil|Alfenta|9737|Schedule II - Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.|Yes
ALFENTANILHYDROCHLORIDECII(500MG) Use and Manufacturing
Analgesic (narcotic).
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
ALFENTANILHYDROCHLORIDECII(500MG)
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