3-Bromobenzanthrone

General procedure: In 2 neck round bottom flask (10 mL) equipped with mercury sealed stirrer, 2 mL of methanol, 1-aminoanthracene-9, 10-dione 1a (1 equiv.) and HBr (2 equiv.) were added at room temperature. To this, H2O2 (2 equiv.) was added over 5 min. The reaction mass was stirred for 8 h. The progress of the reaction was monitored on TLC. The reaction was quenched by adding 2 mL saturated sodium thiosulphate (Na2S2O3) solution and then 2 mL of 5percent sodium bicarbonate (NaHCO3) solution. 10 mL of water was added to the reaction mass and the solid obtained was filtered and washed with water. The crude product thus obtained was further purified using column chromatography with pet ether: ethyl acetate as an eluent to give purified 1-amino-2, 4-dibromoaminoanthracene-9, 10-dione 2a.General procedure: In a 100 mL round bottomed flask equipped with a mercury sealed stirrer, 5 mL acetic acid was placed to which aminoanthracene-9, 10-dione (1, 1 equiv), and KBr (0.5 to 2 equiv) were added under stirring. To this slurry, nonanebis(peroxoic acid) (1 to 2 equiv) was added cautiously over a period of 10 min at room temperature. The reaction mass was stirred at room temperature/50–55 °C and was monitored by TLC. After completion, the reaction mass was poured into 10percent sodium bicarbonate solution to neutralize the acids. The solid obtained was filtered and washed with water till neutral pH was obtained. The crude product was purified by column chromatography on a silica gel with hexane/ethyl acetate (95:5) as an eluent to give purified product 2.

Molecular Weight:309.16
XLogP3:5
Hydrogen Bond Acceptor Count:1
Exact Mass:307.98368
Monoisotopic Mass:307.98368
Topological Polar Surface Area:17.1
Heavy Atom Count:19
Complexity:380
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes