Xanthene-9-carboxylic acid
-
Xanthene-9-carboxylic acid
structure -
-
CAS No:
82-07-5
-
Formula:
C14H10O3
-
Chemical Name:
Xanthene-9-carboxylic acid
-
Synonyms:
9H-Xanthene-9-carboxylic acid;Xanthene-9-carboxylic acid;Xanthenecarboxylic acid;Xanthanoic acid;9-Carboxyxanthene;Xanthine-9-carboxylic acid;NSC 66208;RH 00001
- Categories:
-
CAS No:
Xanthene-9-carboxylic acid Basic Attributes
226.23
226.23
174414
201-394-9
63A81F6A8V
66208
DTXSID70231501
29329990
Characteristics
46.5
2.2
1.3±0.1 g/cm3
217 °C (decomp)
391.3±41.0 °C at 760 mmHg
153.1±21.1 °C
1.646
Insoluble in water.methanol: 0.1 g/mL, clear
Safety Information
2811
3
36/37/38
26-36-37/39-37
Xi
P261-P305 + P351 + P338
H315-H319-H335
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 46 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Xanthene-9-carboxylic acid Use and Manufacturing
The mixture of xanthene alcohol, sodium cyanide, glacial acetic acid, ethanol and water is heated in a closed reaction tank, and the temperature is slowly raised to 95°C, the pressure is 0.1-0.2 MPa, and the reaction is carried out for 6 hours to obtain 9-cyanoxanthene. Then it was refluxed with alkaline solution for 20h, and then acidified with hydrochloric acid to obtain xanthene-9-carboxylic acid.
Xanthene-9-carboxylic Acid is xanthrene derivative that is capable of inhibiting the TTR conformational changes facilitating amyloid fibril formation.
Computed Properties
Molecular Weight:226.23
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:226.062994177
Monoisotopic Mass:226.062994177
Topological Polar Surface Area:46.5
Heavy Atom Count:17
Complexity:280
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
-
3,5-DIBROMO-2-[[[(3,5-DINITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
535965-38-9
-
3,5-DIBROMO-2-[[[[(2-CHLOROPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532386-89-3
-
3,5-DIBROMO-2-[[[(4-METHYL-3-NITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532943-48-9
-
3,5-DIBROMO-2-[[[[3-(2-FURANYL)-1-OXO-2-PROPENYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
586392-09-8
-
3,5-DIBROMO-2-[[[[(2-METHYLPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
531548-30-8
-
2-(1,8-dibromo-16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid Formula
333340-54-8
-
3,5-DIBROMO-2-[[[[3-(PHENOXYMETHYL)BENZOYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
586393-79-5
-
3,5-DIBROMO-2-[[[(4-CHLOROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
531530-32-2
-
What is 2-Cyclopentyl-3-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-oxo-4-isoquinolinecarboxylic acid
400073-92-9
-
What is 9-Octadecenoic acid (9Z)-, compd. with N,N-dimethylcyclohexanamine (1:1)
65122-23-8