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Peppermint oil

pharmaceutical raw materials
Peppermint oil structure

Peppermint oil 

structure
  • CAS No:

    8006-90-4

  • Chemical Name:

    Peppermint oil

  • Synonyms:

    PeppermintOilPure;dementholized;PEPPERMINTOIL,NF;PEPPERMINTESSENCE;Oils,peppermint;FEMA 2848;PEPPERMINT OIL;OIL OF PEPPERMINT;027-50467608;Oils,peppermint;PEPPERMINT OIL FCC;

  • Categories:

    Cosmetic Ingredient  >  Perfuming

Description

Peppermint essential oil is a highly concentrated, natural extract derived from the leaves of the Mentha piperita plant through steam distillation. Renowned for its refreshing, cooling aroma and versatile therapeutic properties, this oil is widely used in aromatherapy, personal care, and natural wellness practices.

Key characteristics:

  • Aroma: Crisp, minty, and invigorating
  • Color: Clear to pale yellow
  • Main Components: Menthol, menthone, and cineole

Benefits & Uses:

  • Promotes mental clarity and focus when diffused
  • Soothes muscle discomfort when diluted and applied topically
  • Supports digestive comfort when used appropriately
  • Adds a refreshing scent to homemade skincare and cleaning products

Caution: Always dilute with a carrier oil before topical application. Avoid contact with eyes and sensitive areas. Not recommended for use on infants or during pregnancy without professional guidance.

100% pure, undiluted, and free from synthetic additives—ideal for holistic health enthusiasts and natural living advocates.

Peppermint oil Basic Attributes

965.5

964.809506

616-900-7

DTXSID6021113

Colorless to pale yellow-greenish liquid

Characteristics

103

0.00000

Liquid

09g/mLat 25°C(lit)

215°C(lit)

196°F

n20/D 1.461(lit.)

Insoluble in water

2-8°C

LD50 orl-rat: 2426 mg/kg JPMSAE 54,1071,65

Strong peppermint odor

PUNGENT TASTE

/ESSENTIAL OIL/ SPECIFIC OPTICAL ROTATION @ 20 °C: ITALIAN -16 TO -23 DEG; FRENCH -10 TO -29 DEG|/ESSENTIAL OIL/ ESTER VALUE: ITALIAN 14-34; FRENCH 14-19; NORTH AMERICAN 14-19|/ESSENTIAL OIL/ ESTER VALUE (AFTER ACETYLATION): ITALIAN 135-174; FRENCH 138-200; NORTH AMERICAN 157-193|/ESSENTIAL OIL/ KETONE CONTENT (AS MENTHONE): ITALIAN 19-30; FRENCH 19-30; NORTH AMERICAN 19-32|For more Other Experimental Properties (Complete) data for PEPPERMINT OIL (9 total), please visit the HSDB record page.

Safety Information

UN 1993 / PGIII

2

23-24/25

SC6125000

Stable. Combustible. Incompatible with strong oxidizing agents.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Essential oils, oleoresins (solvent-free), and natural extractives (including distillates) that are generally recognized as safe for their intended use, within the meaning of section 409 of the Act. Peppermint is included on this list.

|Warning|H315 (90.94%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P272, P273, P280, P302+P352, P305+P351+P338, P321, P332+P313, P333+P313, P337+P313, P362, P363, P391, and P501|Aggregated GHS information provided by 334 companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

...SUBSTITUTION OF LESS IRRITATING SUBSTANCES...REDESIGN OF OPERATIONS...PREVENT CONTACT, PROVISION OF A PHYSICAL BARRIER AGAINST CONTACT, PROPER WASHING FACILITIES, WORK CLOTHING AND STORAGE FACILITIES, PROTECTIVE CLOTHING, AND BARRIER CREAMS. MEDICAL CONTROL...

Toxicity

LD50 Rat oral 2426 mg/kg|LD50 Rat ip 819 mg/kg|LD50 Mouse oral 2490 mg/kg

MENTHA PIPERITA L HUDS...HYBRID FROM...M AQUATICA L & M VIRIDAS L; THE LATTER IS IN TURN A CROSS BETWEEN M SILVESTRIS L & M ROTUNDIFOLIA L. M PIPERITA...TWO VARIETIES: M PIPERITA OFFICINALIS PALLENS CAMUS (WHITE MINT) AND M PIPERITA OFFICINALIS RABESCENS CAMUS (BLACK MINT).|(1984) /Peppermint oil derived from Mentha piperita, and cornmint and peppermint oil derived from Menta arvensis/

Drug Information

Parasympatholytics; Antiemetics|Peppermint oil is extensively used as a ... carminative, antiseptic, and local anesthetic in cold, cough, and other preparations (lozenges, syrups, ointments, tablets, etc.). Enteric coated peppermint oil capsules have been examined as a useful treatment for irritable bowel syndrome; enteric coating allows oil to reach colon in an unmetabolized state; treatment is contraindicated with meals ... and in achlorhydria. Peppermint oil has been recommended as an adjunct to colonoscopy; a diluted suspension of the oil is sprayed on the endoscope to reduce colonic spasm.|TRADITIONAL MEDICINE: Peppermint, spearmint, and their oils reportedly used in both western and eastern cultures as aromatic, stomachic, stimulant, antiseptic, local anesthetic, and antispasmodic in treating indigestion, nausea, sore throat, diarrhea, colds, headaches, toothaches, and cramps. ... /has/ been reported used in cancers.|MEDICATION (VET): CARMINATIVE

Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)|Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

TWO HUMAN PATIENTS WHO CHRONICALLY CONSUMED LARGE QUANTITIES OF PEPPERMINT CANDY PRESENTED WITH IDIOPATHIC ATRIAL FIBRILLATION RESISTANT TO QUINIDINE THERAPY.|Adverse effects: atrial fibrillation, muscle pain, cooling sensation, burning sensation. /From table/|Peppermint and cornmint oils have been reported to have cytotoxic properties.|... Splash of peppermint oil in the eye caused a loss of corneal epithelium, corneal infiltration, release of pigment into the anterior chamber with deposits on the back of the cornea, but in the course of sixteen days the irritation subsided ... .

oleum menthae piperitae

Peppermint oil Use and Manufacturing

Methods of Manufacturing

THE SOL PEPPERMINT ESSENCE IS OBTAINED BY SOLUBILIZATION IN ALCOHOL OF THE TRI-RECTIFIED ESSENTIAL OIL. IT IS USED IN SYRUPS & LIQUEURS WITH YIELDS RANGING FROM 1:100 TO 1:400.|The oil is obtained by steam distillation of the flowering herb Menthax piperita L.|RAW PEPPERMINT ESSENTIAL OIL TO BE USED FOR FOOD FLAVORING MUST BE RECTIFIED. THIS IS COMMONLY KNOWN AS TRI-RECTIFIED PEPPERMINT ESSENTIAL OIL.

Uses

Peppermint oil has always been a popular flavoring agent and can be used in chewing gum, candy, ice cream and sauces. It can also be used in dental preparations and in the treatment of digestive disorders. Because of its cool feeling, it is used in tobacco products. Similarly, this peppermint oil can be used for non-alcoholic beverages, soft drinks and cookies (such as butter cookies).


Odor agents


Air care products

Production

100,000 - 500,000 lb|Approximately 2000 tons annually

INFUSION (2%), FLUID EXTRACT, & TINCTURE (20% IN 70% ETHANOL) /PEPPERMINT/|Not less than 50% total menthol including 5-9% esters calculated as menthyl acetate; menthyl isovalerate, menthone, inactive pinene, L-limonene, cadinene, phellandrene, some acetaldehyde, isovaleric aldehyde, amyl alcohol, dimethyl sulfide.|Grades: Technical; USP, FCC (Food Chemicals Codex)|IT CONTAINS NOT LESS THAN 3% BY VOLUME OF OIL OF PEPPERMINT. /PEPPERMINT EXTRACT/

Soap, cleaning compound, and toilet preparation manufacturing|Oils, peppermint: ACTIVE|ESSENTIAL OIL (TRI-RECTIFIED) IS EXTENSIVELY USED IN FLAVORING CANDIES, BITTER CHOCOLATES, TOBACCO, TOOTHPASTES, & OTHER PRODUCTS. /ESSENTIAL OIL (TRI-RECTIFIED)/|PEPPERMINT OIL...REPORTED USED IN FOLLOWING: NON-ALCOHOLIC BEVERAGES 99 PPM, ALCOHOLIC BEVERAGES 240 PPM, ICE CREAM, ICES, ETC 110 PPM, CANDY 1,200 PPM, BAKED GOODS 300 PPM, GELATINS & PUDDINGS 75-200 PPM; CHEWING GUM 8,300 PPM, MEATS 8.0 PPM, ICINGS 5.0-54 PPM, TOPPING 650 PPM.|THE DRIED FLOWERING TOPS...USED TO PREPARE...PEPPERMINT TEA & THE INFUSION. ...ALSO IN SMALL QUANTITIES IN...LIQUEURS & SPECIAL BITTERS. /PEPPERMINT/|FEMA NUMBER 2848|THE MAIN CONSTITUENTS ARE IDENTICAL IN ALL OIL VARIETIES, BUT THE RELATIVE RATIOS VARY WIDELY. CONSTITUENTS INCLUDE ALPHA- AND BETA-PINENE, LIMONENE, CINEOL, ETHYL AMYLCARBINOL, MENTHONE, ISOMENTHONE MENTHOFURAN, MENTHOL, NEOMENTHOL, ISOMENTHOL MENTHYL ACETATE, & PIPERITONE.

AOAC 920.147. Peppermint, Spearmint, and Wintergreen Extracts. Gas Chromatography Method.

Cosmetics -> Deodorant; Masking; Refreshing; Tonic

Computed Properties

Molecular Weight:965.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:964.80950578
Monoisotopic Mass:964.80950578
Topological Polar Surface Area:103
Heavy Atom Count:69
Complexity:953
Undefined Atom Stereocenter Count:11
Covalently-Bonded Unit Count:6
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • AMNEAL PHARMACEUTICALS LLC

    United States United States
    Active
  • WILD FLAVORS INC

    United States United States
    Active
  • SYMRISE INC

    United States United States
    Active

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