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Chloroform

Chloroform structure

CAS No:
8013-54-5
Formula:
CHCl3
Chemical Name:
Chloroform
Synonyms:
Methane,trichloro-;Chloroform;Trichloromethane;Trichloroform;R 20;R 20 (refrigerant);HCC 20;F 20;NSC 77361;8013-54-5
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

Chloroform is a noncombustible, clear, colorless liquid with a pleasant, sweet odor. The Odor Threshold is 12 ppm.

Chloroform Basic Attributes

Molecular Weight：

119.369

Exact Mass：

119.38

EC Number：

200-663-8

Characteristics

PSA：

XLogP3：

1.97

Appearance：

Chloroform appears as a clear colorless liquid with a characteristic odor. Denser (12.3 lb / gal) than water and slightly soluble in water. Hence sinks in water. Nonflammable under most conditions, but burns under extreme conditions. May cause illness by inhalation, skin absorption or ingestion. Used as a solvent, to make other chemicals, as a fumigant.

Density：

1.4835 g/cm³ @ Temp: 20 °C

Melting Point：

-63.2 °C

Boiling Point：

61.2 °C

Flash Point：

None (EPA, 1998)

Water Solubility：

(77°F): 0.5%

Storage Conditions：

Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ) that bears appropriate label. An inventory should be kept, showing quantity of carcinogen & date it was acquired Facilities for dispensing should be contiguous to storage area.

Vapor Pressure：

Vapour pressure, kPa at 20°C: 212

Vapor Density：

4.12

Flammability characteristics：

Noncombustible Liquid

Odor：

Pleasant, etheric, nonirritating

Taste：

Sweet taste

Safety Information

Packing level：

III

Hazard category：

Transport codes：

1888

hazard class code：

22-38-40-48/20/22

safety instructions：

(2)-36/37

RTECS Number：

FS9100000

Marks：

Storage features：

Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Ventilation along the floor.

Stability/Shelf Life：

The following shelf lives were recommended: chloroform soln and non-sedimented mixtures could be stored in well-closed well-filled containers for 2 mo at ambient temp; when stored in partially-filled containers periodically opened the shelf-life should not exceed 2 wk; sedimented mixtures could be stored for 2 mo in well-closed well-filled containers, but because loss of chloroform could be expected in containers periodically opened such mixtures should be prepared as required or packed in their

Precautionary statement(s)：

P201, P202, P260, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P311, P314, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H302