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Home > Encyclopedia > (3R,4S,5S,7R,9E,11R,12R)-12-Ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione

(3R,4S,5S,7R,9E,11R,12R)-12-Ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione

(3R,4S,5S,7R,9E,11R,12R)-12-Ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione structure

(3R,4S,5S,7R,9E,11R,12R)-12-Ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione 

structure
  • CAS No:

    81644-19-1

  • Formula:

    C17H28O4

  • Chemical Name:

    (3R,4S,5S,7R,9E,11R,12R)-12-Ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione

  • Synonyms:

    Oxacyclododec-9-ene-2,8-dione,12-ethyl-4-hydroxy-3,5,7,11-tetramethyl-,(3R,4S,5S,7R,9E,11R,12R)-;Methynolide,10-deoxy-;(3R,4S,5S,7R,9E,11R,12R)-12-Ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione;Oxacyclododec-9-ene-2,8-dione,12-ethyl-4-hydroxy-3,5,7,11-tetramethyl-,[3R-(3R*,4S*,5S*,7R*,9E,11R*,12R*)]-;(+)-10-Deoxymethynolide;10-Deoxymethynolide

  • Categories:

    Organic Chemistry  >  Lactones

Description

ChEBI: A macrolide that consists of oxacyclododec-9-ene-2,8-dione bearing four methyl substituents at positions 3, 5, 7 and 11 as well as a hydroxy group at position 4 and an ethyl substituent at position 12. The aglycone of the macrolide antibiotic 10-deoxymethy ycin.


10-deoxymethynolide is a macrolide that consists of oxacyclododec-9-ene-2,8-dione bearing four methyl substituents at positions 3, 5, 7 and 11 as well as a hydroxy group at position 4 and an ethyl substituent at position 12. The aglycone of the macrolide antibiotic 10-deoxymethymycin. It has a role as a metabolite.

(3R,4S,5S,7R,9E,11R,12R)-12-Ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione Basic Attributes

296.407

296.40

Characteristics

63.6

3.3

Drug Information

10-deoxymethynolide

(3R,4S,5S,7R,9E,11R,12R)-12-Ethyl-4-hydroxy-3,5,7,11-tetramethyloxacyclododec-9-ene-2,8-dione Use and Manufacturing

Polyketides [PK] -> Macrolides and lactone polyketides [PK04]

Computed Properties

Molecular Weight:296.4
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:296.19875937
Monoisotopic Mass:296.19875937
Topological Polar Surface Area:63.6
Heavy Atom Count:21
Complexity:402
Defined Atom Stereocenter Count:6
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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