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Home > Encyclopedia > 4-Hydroxymidazolamb-D-Glucuronide

4-Hydroxymidazolamb-D-Glucuronide

4-Hydroxymidazolamb-D-Glucuronide structure

4-Hydroxymidazolamb-D-Glucuronide 

structure
  • CAS No:

    81256-82-8

  • Formula:

    C24H21ClFN3O7

  • Chemical Name:

    4-Hydroxymidazolamb-D-Glucuronide

  • Synonyms:

    4-Hydroxymidazolam -D-Glucuronide;4-Hydroxymidazolam b-D-Glucuronide;4-Hydroxy MidazolaM β-D-Glucuronide (Mixture of DiastereoMers);8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-yl -D-Glucopyranosiduronic Acid;8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-yl b-D-Glucopyranosiduronic Acid

Description

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4-hydroxymidazolam beta-D-glucuronide is a beta-D-glucosiduronic acid that is beta-D-glucuronic acid in which the anomeric hydroxyl hydrogen has been replaced by a 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-yl group. It is the glucuronidated conjugate of the midazolam metabolite, 4-hydroxymidazolam. It has a role as a drug metabolite and a human urinary metabolite. It is a beta-D-glucosiduronic acid, a monosaccharide derivative, an imidazobenzodiazepine, a member of monofluorobenzenes and an organochlorine compound. It derives from a 4-hydroxymidazolam.

4-Hydroxymidazolamb-D-Glucuronide Basic Attributes

517.89100

517.10500

DTXSID70857806

Characteristics

146.63000

1.16720

>205ºC (dec.)

Controlled Substance, -20ºC Freezer, Under Inert Atmosphere

4-Hydroxymidazolamb-D-Glucuronide Use and Manufacturing

A metabolite of midazolam The metabolite of Midazolam (M343000).

Computed Properties

Molecular Weight:517.9
XLogP3:2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:517.1052059
Monoisotopic Mass:517.1052059
Topological Polar Surface Area:147
Heavy Atom Count:36
Complexity:855
Defined Atom Stereocenter Count:5
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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