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Home > Encyclopedia > 2-Amino-3-phosphonopropionic acid

2-Amino-3-phosphonopropionic acid

2-Amino-3-phosphonopropionic acid structure

2-Amino-3-phosphonopropionic acid 

structure
  • CAS No:

    5652-28-8

  • Formula:

    C3H8NO5P

  • Chemical Name:

    2-Amino-3-phosphonopropionic acid

  • Synonyms:

    Alanine,3-phosphono-;3-Phosphonoalanine;α-Amino-β-phosphonopropionic acid;Phosphonic acid,(2-amino-2-carboxyethyl)-;2-Amino-3-phosphonopropionic acid;DL-2-Amino-2-carboxyethylphosphonic acid;DL-2-Amino-3-phosphonopropionic acid;DL-2-Amino-3-phosphonopropionate;(±)-2-Amino-3-phosphonopropionic acid;3-Phosphono-DL-alanine;(±)-2-Amino-3-phosphonopropanoic acid;NSC 30078;2-Amino-3-phosphonopropanoic acid;20263-06-3

Description

Solid


Solid


2-amino-3-phosphonopropanoic acid is a non-proteinogenc alpha-amino acid that is alanine in which one of the hydrogens of the terminal methyl group has been replaced by a dihydroxy(oxido)-lambda(5)-phosphanyl group. It has a role as a metabotropic glutamate receptor antagonist and a human metabolite. It is a non-proteinogenic alpha-amino acid, a member of phosphonic acids and an alanine derivative.

2-Amino-3-phosphonopropionic acid Basic Attributes

169.073081

169.07

133887|30078

Characteristics

121

-5.2

Solid

1.763g/cm3

481.6ºC at 760mmHg

245.1ºC

Safety Information

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

H315

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (See all compounds classified as Excitatory Amino Acid Antagonists.)

2-amino-3-phosphono-propionic acid

Computed Properties

Molecular Weight:169.07
XLogP3:-5.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:169.01400935
Monoisotopic Mass:169.01400935
Topological Polar Surface Area:121
Heavy Atom Count:10
Complexity:174
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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