2-(2-Aminoethoxy)ethanol
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2-(2-Aminoethoxy)ethanol
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CAS No:
929-06-6
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Formula:
C4H11NO2
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Chemical Name:
2-(2-Aminoethoxy)ethanol
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Synonyms:
Ethanol, 2-(2-aminoethoxy)-;2-(2-AMinoethoxy)ethanol, 98% 100ML;2-(2-AMinoethoxy)ethanol, 98% 1LT;2-(2-Aminoethoxy)ethanol,98%;Diethylene Glycolamine Diglycolamine Ethylene Glycol Mono(2-aminoethyl) Ether O-(2-Hydroxyethyl)ethanolamine;2-(2-AMINOETHOXY)ETHANOL FOR SYNTHESIS;O-(2-Hydroxyethyl)ethanolamine DGA;1-Amino-2-(2-hydroxyethoxy)ethane
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CAS No:
Description
colourless to faintly yellow liquid 2-(2-Aminoethoxy)ethanol is a combustible, colorless to light yellow, thick liquid. Fishy odor
2-(2-aminoethoxy)ethanol appears as a colorless liquid with a faint fishlike odor. Combustible but difficult to ignite. Corrosive to tissue. Combustion produces toxic oxides of nitrogen.|Liquid
2-(2-aminoethoxy)ethanol appears as a colorless liquid with a faint fishlike odor. Combustible but difficult to ignite. Corrosive to tissue. Combustion produces toxic oxides of nitrogen.
Amino-PEG2-alcohol is a short PEG linker containing an amino group with a hydroxyl group. The amino (NH2) group is reactive with activated NHS esters, carbonyls (ketone, aldehyde) etc.
Moderately toxic by skin contact. Mildly toxic by ingestion. Severe eye and skin irritant. Corrosive and a powerful irritant. When heated to decomposition it emits toxic fumes of NOx,.
2-(2-Aminoethoxy)ethanol Basic Attributes
105.14
105.14
906728
213-195-4
6R5Y84T8W9
86108
3055
TSCA listed
DTXSID6027341
Yellow
29221980
Characteristics
55.48000
-1.37
Yellow Crystalline Powder and or Chunks
1.05
-12.5 °C
218-224 °C(lit.)
>230 °F
n20/D1.460
miscible
Store below +30°C.
<0.1 hPa (20 °C)
LD50 orally in Rabbit: 3000 mg/kg LD50 dermal Rabbit > 3000 mg/kg
Not classified
2.0-15.5%(V)
slightly viscous liq., amine odor
10.2 (10g/l, H2O, 20℃)
14.37±0.10(Predicted)
6.1×103mol/(m3Pa) at 25℃, Nguyen (2013)
Water soluble.
Alcohols and Polyols
2-(2-AMINOETHOXY) ETHANOL is an aminoalcohol. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.
370 °C
Store below +30°C.
Safety Information
III
8
UN 3055 8/PG 3
1
C
26-36/37/39-45-24/25
KJ6125000
C
Treasury is ventilated, low temperature and dry; stored separately from acid and oxidant
Stable. Incompatible with acids, strong oxidizing agents. Reacts with carbon dioxide.
P280-P305 + P351 + P338-P310
21-34
Reacts with oxidizers, strong acids; and chemically active metals, such as potassium, sodium, magnesium and zinc.
UN 3055
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
|Danger|H290 (46.09%): May be corrosive to metals [Warning Corrosive to Metals]|P234, P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P390, P404, P405, and P501|Aggregated GHS information provided by 959 companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: SMALL FIRE: Dry chemical, CO2 or water spray. LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal; do not scatter the material. FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2016)
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. (ERG, 2016)
/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas.|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.|For more DOT Emergency Guidelines (Complete) data for 2-(2-AMINOETHOXY)ETHANOL (8 total), please visit the HSDB record page.
No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
STRONG IRRITANT TO TISSUE.
Drug Information
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim calm and warm. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. (ERG, 2016)
STRONG IRRITANT TO TISSUE.
2-(2-aminoethoxy)ethanol
2-(2-Aminoethoxy)ethanol Use and Manufacturing
Agricultural chemicals (non-pesticidal)
Agricultural products (non-pesticidal)
2-(2-Aminoethoxy)ethanol is used mainly in stripper solutions for applications in electronics, in gas treating to remove carbon dioxide and hydrogen sulfide, and in coolants/lubricants for metal working applications. Other applications of aminoethoxyethanol (ADG) include, inter alia, crop protection products, surfactants and colorants. It is also used as a selective solvent for recovery of aromatics from refinery streams and in preparation of foam stabilizers, wetting and emulsifying agents.
2-(2-Aminoethoxy)ethanol is commonly used as a spacer/linker in the synthesis of bioconjugate materials for applications such as drug delivery and protein labeling. It is also employed as a receptor chain in the preparation of carboxamidoquinoline based water-soluble, ratiometric fluorescent zinc sensor.
10,000,000 - 50,000,000 lb
Agriculture, forestry, fishing and hunting|Ethanol, 2-(2-aminoethoxy)-: ACTIVE
Health Hazards -> Corrosives
Computed Properties
Molecular Weight:105.14
XLogP3:-1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:105.078978594
Monoisotopic Mass:105.078978594
Topological Polar Surface Area:55.5
Heavy Atom Count:7
Complexity:32.9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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