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2,2′-(Ethylenedioxy)bis(ethylamine)

2,2′-(Ethylenedioxy)bis(ethylamine) structure

CAS No:
929-59-9
Formula:
C6H16N2O2
Chemical Name:
2,2′-(Ethylenedioxy)bis(ethylamine)
Synonyms:
Ethanamine,2,2′-[1,2-ethanediylbis(oxy)]bis-;Ethylamine,2,2′-(ethylenedioxy)bis-;2,2′-[1,2-Ethanediylbis(oxy)]bis[ethanamine];3,6-Dioxa-1,8-octanediamine;1,8-Diamino-3,6-dioxaoctane;1,2-Bis(2-aminoethoxy)ethane;Jeffamine EDR 148;2,2′-(Ethylenedioxy)bis(ethylamine);Ethylene glycol bis(2-aminoethyl) ether;2,2′-(Ethylenedioxy)diethylamine;EDR 148;DA 10;XTJ 504;Daitocurar J 5030;NSC 28972;2-[2-(2-Aminoethoxy)ethoxy]ethylamine;O,O′-Bis(2-aminoethyl)ethylene glycol;2-(2-(2-Aminoethoxy)ethoxy)ethanamine;1,8-Diamine-3,6-dioxaoctane;2-[2-(2-Aminoethoxy)ethoxy]ethan-1-amine;1,10-Diaza-4,7-dioxadecane;Jeffamine 148;2,2′-(Ethan-1,2-diylbis(oxy))diethanamine;2,2′-(Ethane-1,2-diylbis(oxy))diethanamine;Epic 91B;2,2-(Ethylenedioxy)diethylamine;O,O′-Bis(2-aminoethyl)-1,2-ethanediol;2,2′-(Ethan-1,2-diylbis(oxy))bis(ethan-1-amine);2,2′-(Ethane-1,2-diylbis(oxy))bis(ethan-1-amine);2,2′-(Ethylenedioxy)bisethylenediamine
Categories:
Chemical Reagents > Organic Reagents

Description

PROTAC Linker 19 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 19 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Liquid

2,2′-(Ethylenedioxy)bis(ethylamine) Basic Attributes

Molecular Weight：

148.2

Exact Mass：

148.20

EC Number：

213-203-6

UNII：

R41ZT4UF34

NSC Number：

28972

DSSTox ID：

DTXSID9044742

HScode：

2922199090

Characteristics

PSA：

70.5

XLogP3：

-2

Appearance：

Liquid

Density：

1.0±0.1 g/cm3

Boiling Point：

95-105 °C @ Press: 5 Torr

Flash Point：

104.3±15.5 °C

Refractive Index：

1.460

Water Solubility：

Soluble in 0.4 parts water.

Safety Information

Packing level：

Ⅱ

Hazard category：

Transport codes：

2735

wgk germany：

hazard class code：

safety instructions：

S23-S26-S36/37/39-S45

Marks：

C:Corrosive;

Precautionary statement(s)：

P261-P280-P305 + P351 + P338-P310

Hazard Statements：

H302-H314-H317-H334

GHS Classification：

|Danger|H302 (98.84%): Harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P272, P280, P285, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P304+P341, P305+P351+P338, P310, P312, P321, P330, P333+P313, P342+P311, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 344 companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

2,2'-(ethylenedioxy)diethylamine

2,2′-(Ethylenedioxy)bis(ethylamine) Use and Manufacturing

Uses

Adhesives and sealant chemicals

Manufacturing Info：

Adhesive manufacturing|Ethanamine, 2,2'-[1,2-ethanediylbis(oxy)]bis-: ACTIVE|PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Computed Properties

Molecular Weight:148.20
XLogP3:-2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:148.121177757
Monoisotopic Mass:148.121177757
Topological Polar Surface Area:70.5
Heavy Atom Count:10
Complexity:53.7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of 2,2′-(Ethylenedioxy)bis(ethylamine)

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
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2,2′-(Ethylenedioxy)bis(ethylamine)

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