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Home > Encyclopedia > Butanoic acid, 2-(hydroxyimino)-3-oxo-, ethyl ester

Butanoic acid, 2-(hydroxyimino)-3-oxo-, ethyl ester

Butanoic acid, 2-(hydroxyimino)-3-oxo-, ethyl ester structure

Butanoic acid, 2-(hydroxyimino)-3-oxo-, ethyl ester 

structure
  • CAS No:

    5408-04-8

  • Formula:

    C6H9NO4

  • Chemical Name:

    Butanoic acid, 2-(hydroxyimino)-3-oxo-, ethyl ester

  • Synonyms:

    Butanoic acid,2-(hydroxyimino)-3-oxo-,ethyl ester;Butyric acid,2,3-dioxo-,ethyl ester,2-oxime;Butyric acid,α,β-dioxo-,ethyl ester α-oxime;Ethyl α-isonitrosoacetoacetate;Ethyl 2-(hydroxyimino)acetoacetate;Ethyl 2-oximinoacetoacetate;Ethyl α-(hydroxyimino)acetoacetate;2-(Hydroxyimino)-3-oxobutyric acid ethyl ester;Ethyl α-oximinoacetoacetate;Ethyl 2-(hydroxyimino)-3-ketobutyrate;Ethyl 2-(hydroxyimino)-3-oxobutanoate;2-Hydroxyimino-3-oxobutanoic acid ethyl ester;NSC 10758

Butanoic acid, 2-(hydroxyimino)-3-oxo-, ethyl ester Basic Attributes

159.14

159.14

611-092-2

2928000090

Characteristics

75.96000

-0.03130

1.22g/cm3

45-47 °C

136-137 °C @ Press: 5 Torr

114.7ºC

1.476

Safety Information

IRRITANT

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Butanoic acid, 2-(hydroxyimino)-3-oxo-, ethyl ester Use and Manufacturing

Methods of Manufacturing

It is prepared by the reaction of ethyl acetoacetate and sodium nitrite under acidic conditions.

Uses

The intermediate of cimetidine.

Computed Properties

Molecular Weight:159.14
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:159.05315777
Monoisotopic Mass:159.05315777
Topological Polar Surface Area:76
Heavy Atom Count:11
Complexity:197
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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