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MTP-PE

MTP-PE structure

MTP-PE 

structure
  • CAS No:

    83461-56-7

  • Formula:

    C59H109N6O19P

  • Chemical Name:

    MTP-PE

  • Synonyms:

    L-Alaninamide,N-(N-acetylmuramoyl)-L-alanyl-D-α-glutaminyl-N-[(7R)-4-hydroxy-4-oxido-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacos-1-yl]-;L-Alaninamide,N-(N-acetylmuramoyl)-L-alanyl-D-α-glutaminyl-N-[4-hydroxy-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacos-1-yl]-,P-oxide,(R)-;N-(N-Acetylmuramoyl)-L-alanyl-D-α-glutaminyl-N-[(7R)-4-hydroxy-4-oxido-10-oxo-7-[(1-oxohexadecyl)oxy]-3,5,9-trioxa-4-phosphapentacos-1-yl]-L-alaninamide;CGP 19835;Muramoyl tripeptide phosphatidylethanolamine;MTP-PE;MLV 19835;Mifamurtide;L-MTP-PE;98366-77-9;100680-90-8;119590-64-6;84804-97-7;85232-96-8;90365-61-0;159593-43-8

  • Categories:

    Active Pharmaceutical Ingredients  >  Other Chemical Drugs

Description

Mifamurtide(CGP19835; MTP-PE) is a drug against osteosarcoma.Target: OthersMifamurtide is an immunomodulator with antitumor effects that appear to be mediated via activation of monocytes and macrophages. Mifamurtide is generally well tolerated; adverse events attributed to administration of the drug include chills, fever, headache, nausea, and myalgias. Based on the available data, mifamurtide can be considered for inclusion in treatment protocols for localized osteosarcoma [1]. Mifamurt


Mifamurtide is a dipeptide.

MTP-PE Basic Attributes

1237.499

1237.50

Characteristics

385.91000

10.98

1.2±0.1 g/cm3

1.530

Safety Information

3

MTP-PE Use and Manufacturing

Osteosarcoma.

Computed Properties

Molecular Weight:1237.5
XLogP3:9
Hydrogen Bond Donor Count:10
Hydrogen Bond Acceptor Count:19
Rotatable Bond Count:54
Exact Mass:1236.74851227
Monoisotopic Mass:1236.74851227
Topological Polar Surface Area:376
Heavy Atom Count:85
Complexity:1960
Defined Atom Stereocenter Count:9
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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