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Phencyclidine hydrochloride

Phencyclidine hydrochloride structure

Phencyclidine hydrochloride 

structure
  • CAS No:

    956-90-1

  • Formula:

    C17H25N.ClH

  • Chemical Name:

    Phencyclidine hydrochloride

  • Synonyms:

    Piperidine,1-(1-phenylcyclohexyl)-,hydrochloride (1:1);Piperidine,1-(1-phenylcyclohexyl)-,hydrochloride;GP 121;CI 395;Elysion;Phencyclidine hydrochloride;Phenylcyclidine hydrochloride;1-(1-Phenylcyclohexyl)piperidine hydrochloride;Sernyl hydrochloride;Sernyl;Sernylan;NIH 9580;MCV 4158;Phencyclidine monohydrochloride;PCP hydrochloride;NSC 40902

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Crystalline Solid


Sernylan is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.|A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.

Phencyclidine hydrochloride Basic Attributes

279.84800

279.17500

7471

2933399090

Characteristics

3.24000

5.07180

233-235 °C

340ºC at 760 mmHg

144.5ºC

In water, 28.37 mg/L at 25 deg C (est)

Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

1.91X10-4 mm Hg at 25 deg C (est)

LD50 orally in mice: 76.5 mg/kg (Bailey)

Safety Information

I

6.1(a)

UN 2811 6.1/PG 3

3

25

36/37-45

TN2272600

T

P301 + P310

H301

Drug Information

Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise. (See all compounds classified as Hallucinogens.)|Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)|Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (See all compounds classified as Excitatory Amino Acid Antagonists.)

1-(1-Phenylcyclohexyl)piperidine

Phencyclidine|PCP, Sernylan|7471|Schedule II - Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.|No

Phencyclidine hydrochloride Use and Manufacturing

Anesthetic (intravenous). Controlled substance (depressant). Controlled substance (depressant). Anesthetic (intravenous).

Computed Properties

Molecular Weight:279.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:279.1753775
Monoisotopic Mass:279.1753775
Topological Polar Surface Area:4.4
Heavy Atom Count:19
Complexity:242
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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