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Home > Encyclopedia > Opipramol hydrochloride

Opipramol hydrochloride

Opipramol hydrochloride structure

Opipramol hydrochloride 

structure
  • CAS No:

    909-39-7

  • Formula:

    C23H29N3O.2ClH

  • Chemical Name:

    Opipramol hydrochloride

  • Synonyms:

    1-Piperazineethanol,4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-,hydrochloride (1:2);1-Piperazineethanol,4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-,dihydrochloride;5H-Dibenz[b,f]azepine,1-piperazineethanol deriv.;G 33040;4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol dihydrochloride;5-[γ-(β-Hydroxyethylpiperazino)propyl]-5H-dibenzo[b,f]azepine dihydrochloride;Opipramol hydrochloride;Insidon;Pramolan;Insidone;Dinsidon;Nisidana

Description

A tricyclic antidepressant with actions similar to AMITRIPTYLINE.

Opipramol hydrochloride Basic Attributes

436.41800

435.18400

213-000-2

B49OBI656M

DTXSID5045752

Characteristics

29.95000

4.85330

229-230 °C

Safety Information

UN 3077 9 / PGIII

3

22-50/53

60-61

TL9100000

Xn,N

P273-P501

H302-H410

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P273, P301+P312, P330, P391, and P501|Aggregated GHS information provided by 42 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (See all compounds classified as Adrenergic Uptake Inhibitors.)|Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. (See all compounds classified as Antidepressive Agents, Tricyclic.)

Hydrochloride, Opipramol

Opipramol hydrochloride Use and Manufacturing

antidepressant, antipsychotic;'sigma antagonist

Computed Properties

Molecular Weight:436.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:435.1844180
Monoisotopic Mass:435.1844180
Topological Polar Surface Area:30
Heavy Atom Count:29
Complexity:448
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

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