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Carboxymethylcellulose sodium salt

pharmaceutical raw materials
Carboxymethylcellulose sodium salt structure

Carboxymethylcellulose sodium salt 

structure
  • CAS No:

    9085-26-1

  • Formula:

    C8H16NaO8

  • Chemical Name:

    Carboxymethylcellulose sodium salt

  • Synonyms:

    CARBOXYMETHYL CELLULOSE SODIUM;CARBOXYMETHYLCELLULOSE SODIUM SALT;CELLULOSE, CARBOXY METHYL, SODIUM SALT;CELLULOSE GLYCOLIC ACID SODIUM SALT;CMC 7HF;CMC 7LF;CMC 7MF;AQUACIDE I

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Sodium carboxymethyl cellulose is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.


Carboxymethylcellulose sodium salt: a kind of cellulose derivate.Carboxymethylcellulose sodium salt (Sodium carboxymethyl cellulose or CMC) is one of the most essential products of cellulose ethers, which are formed by natural cellulose modification as a kind of cellulose derivate with an ether structure. Because the acid form of CMC has poor water solubility, it is usually preserved as sodium carboxymethylcellulose, widely used in many industries and regarded as monosodium glutamate in industry. It is a non-toxic and biodegradable water-soluble polymer used as an adhesive and cross-linking agent in the pharmaceutical industry. CMC could be used as flocculating agent, chelating agent, emulsifier, thickening agent, water-retaining agent, sizing agent, film-forming material, and so on. CMC is also widely applied in electronics, pesticides, leather, plastics, printing, ceramics, and the daily-use chemical industry. Moreover, due to its excellent properties, wide application, and developing potential fields, CMC has broad application prospects.

Carboxymethylcellulose sodium salt Basic Attributes

0

263.074

618-378-6

Off-White to Pale Beige

Characteristics

156

Sodium carboxymethyl cellulose (CMC) is an anionic cellulose ether, with white or slightly yellow flocculent fiber powder or white powder appearance, odorless, tasteless, non-toxic; easily soluble in cold water or hot water, forming a certain viscosity clear solution[2]. The solution is neutral or slightly alkaline, insoluble in ethanol, ether, isopropanol, acetone and other organic solvents, soluble in 60% water-containing ethanol or acetone solution. It is hygroscopic, stable to light and heat, the viscosity decreases with the increase of temperature, the solution is stable at pH 2-10, pH is lower than 2, there is solid precipitation, and the viscosity decreases when pH is higher than 10. The discoloration temperature is 227℃, the carbonization temperature is 252℃, and the surface tension of 2% aqueous solution is 71mn/n.

OtherSolid

1.59 g/cm3

274 °C (dec.)

Yields a viscous colloidal solution with water. Insoluble in ethanol

Not less than 5,0 and not more than 8,5 (1 % colloidal solution)

Room Temperature

Safety Information

1

FJ5950000

P261, P264, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, P501

H315

Carboxymethylcellulose sodium salt Use and Manufacturing

Sodium carboxymethylcellulose is readily soluble in water and is insoluble in organic solvents. The material is used as a soil-suspending agent in detergents, suspending agent in latex paints and as an adhesive; it is also used as a stabilizer in food products such as ice cream.

Related Drugs

Registered Holders

  • ANHUI SUNHERE PHARMACEUTICAL EXCIPIENTS CO LTD

    United States United States
    Active
  • AQUALON CO

    United States United States
    Inactive
  • METSA SPECIALTY CHEMICALS BV

    United States United States
    Inactive

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