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Hydroxyethyl starch

Hydroxyethyl starch structure

CAS No:
9005-27-0
Formula:
C2H6O2.xUnspecified
Chemical Name:
Hydroxyethyl starch
Synonyms:
Starch,2-hydroxyethyl ether;Hydroxyethyl starch;Starch hydroxyethyl ether;Hespander;Ethylex 2020;O-(Hydroxyethyl)starch;O-(2-Hydroxyethyl)starch;Penford 260;Penford 290;Tapioca starch hydroxyethyl ether;2-Hydroxyethyl starch;Essex Gum 1360;2-Hydroxyethyl starch ether;Penford P 208;Penford 280;Essex 1360;Plasmasteril;Amaizo 742D;HAES-steril;Hespan;Bohramyl;Hetastarch;Amaizo 745D;Bohramyl CR;Ethylex 2030;Pen-Cote;Clineo 712D;Ethylex Gum 2020;Ethylex Gum 2030;Ethylex 3095;Pentastarch;Volex;Pentaspan;PG 280;Pentafraction;Polaris Gum;Polaris Gum LV;Penford 270;QYH 1;Oxethamyl;HET;Unique Gum 3010;PG 380;Ethylex 2025;Penford 460;Coatmaster K;Coatmaster K 500;Coatmaster K 520;Coatmaster K 530;Coatmaster K 540;Coatmaster K 550;Coatmaster K 560;Coatmaster K 570;Coatmaster K 580;Coatmaster K 59F;Coatmaster K 92F;Volekam;Penford Gum 295;Penford Gum 280;Penford 295;Penford Gum 260;Elohes;Coatmaster K 592;Penford Gum 200;Penford 200;Pentalyte;Penford 230;Penford 300;Solfarex A 85;PG 295;Ethylex 2095;Hydroxyethylated starch;Voluven;Penford Gum 290;Elohast;Expafusion;Expafusin;FG 280;PenFilm HV 421182;Penford Gum 380;Astro Gum 3020;Penford 380;Penford Gum 270;Ethylex 2035;Coatmaster K 95F;Ethylex 2065;Solfarex A 55;Film Flex 70;Film Flex 20;Coatmaster K 55F;Coatmaster K 54F;Coatmaster K 56F;Coatmaster K 57F;Coatmaster K 58F;Ethylex 2005;Ethylex 2040;HE 200/0.5;HES 130/0.4;Film Flex 60;9057-07-2;39363-84-3;39363-85-4;62253-20-7;73666-73-6;87140-13-4;115252-32-9;204144-00-3;936087-55-7;936087-60-4;1415795-12-8
Categories:
Active Pharmaceutical Ingredients > Blood System Drugs

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Description

DS 0.7;

Hydroxyethyl starch Basic Attributes

Molecular Weight：

580.577

Exact Mass：

580.257874

EC Number：

1308068-626-2

DSSTox ID：

DTXSID3046829

ATC Code：

B - Blood and blood forming organs

Characteristics

PSA：

267

Storage Conditions：

-20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

RTECS Number：

WI0410000

Hydroxyethyl starch Use and Manufacturing

Uses

Blood volume expander, used for rehydration of various operations, traumatic blood loss, toxic shock, etc.

Manufacturing Info：

Starch, 2-hydroxyethyl ether: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).

Use Classification：

EPA Safer Chemical Functional Use Classes -> Polymers|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Computed Properties

Molecular Weight:580.6
Hydrogen Bond Donor Count:10
Hydrogen Bond Acceptor Count:17
Rotatable Bond Count:17
Exact Mass:580.25784993
Monoisotopic Mass:580.25784993
Topological Polar Surface Area:267
Heavy Atom Count:39
Complexity:497
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Drug Function and Efficacy

After intravenous infusion, this product stays in the blood for a long time, increasing plasma osmotic pressure, increasing tissue fluid reflux, rapidly increasing blood volume, diluting blood, and increasing the negative charge of cell membranes, causing aggregated cells to disaggregate, reducing systemic blood viscosity, and improving microcirculation.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Hydroxyethyl starch 40 sodium chloride injection
Ingredients	Hydroxyethyl starch 40.
Indication	Not yet clear.
Specifications	500ml: 4030g hydroxyethyl starch and 4.5g sodium chloride

Hydroxyethyl starch 20% sodium chloride injection
Ingredients	Hydroxyethyl starch 20.
Indication	Not yet clear.
Specifications	500ml: 30g hydroxyethyl starch 20 and 4.5g sodium chloride

Hydroxyethyl starch 20% sodium chloride injection
Ingredients	Hydroxyethyl starch 20.
Indication	Not yet clear.
Specifications	250ml: 15g hydroxyethyl starch 20 and 2.25g sodium chloride
Manufacturer	Qingzhou Yaowang Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

Shandong Qidu Pharmaceutical Co., Ltd.

China
Active
Mudanjiang Wanwei Pharmaceutical Co., Ltd.

China
Active
Sichuan Xin Kai Yuan Pharmaceutical Co., Ltd.

China
Active

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