Difluoxacin hydrochloride
-
Difluoxacin hydrochloride
structure -
-
CAS No:
91296-86-5
-
Formula:
C21H20ClF2N3O3
-
Chemical Name:
Difluoxacin hydrochloride
-
Synonyms:
DIFLUOXACIN HYDROCHLORIDE;Difluoxacin HCL;6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monohydrochloride;-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;6-Fluoro-1-(4-fluorophenyl);-7-(4-methylpiperazin-1-yl);Double difloxacin hydrochloride
-
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs
-
CAS No:
Description
Difloxacin hydrochloride is a broad-spectrum antibacterial drug. Difloxacin hydrochloride inhibits bacterial DNA gyrase and exhibits a concentration-dependant bactericidal effect by interference with the activity of DNA gyrase and topoisomerase IV[1].
Difloxacin is a fluoroquinolone antibiotic. It is active against isolates of anaerobic bacteria, includingB. fragilis, as well asFusobacteriumandActinomycesspecies with MIC values ranging from ≤0.125 to 8 μg/ml. It eliminatesE. coliandB. fragilisinfection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.
Off-White to Pale Yellow Solid
Difluoxacin hydrochloride Basic Attributes
435.85
435.116119
1806241-263-5
XJ0260HJ0O
759646
DTXSID2046599
White to off-white
Characteristics
64.1
3.52380
off-white to pale yellow solid
1.409 g/cm3
>245°C (dec.)
595.5ºC at 760 mmHg
313.9ºC
1.629
soluble in aqueous buffer
0-6°C
Inert atmosphere,Room Temperature
Drug Information
1-(4-fluorophenyl)-6-fluoro-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
Difluoxacin hydrochloride Use and Manufacturing
A fluoroquinolone antibacterial structurally related to norfloxacin.
antibacterial, DNA gyrase inhibitor
Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
Computed Properties
Molecular Weight:435.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:435.1161255
Monoisotopic Mass:435.1161255
Topological Polar Surface Area:64.1
Heavy Atom Count:30
Complexity:672
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Recommended Suppliers of Difluoxacin hydrochloride
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 91296-86-5Grade: Industrial GradeContent: 99% -
![China]()
CN
3 YRS
Business licensedTrader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVEInquiryCAS No.: 91296-86-5Grade: Pharmaceutical GradeContent: 99%
Learn More Other Chemicals
-
4H-1-Benzopyran-4-one, 2-[4-[3-(dibutylamino)propoxy]-3,5-dimethylbenzoyl]-, hydrochloride (1:1)
67652-33-9
-
Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester, hydrochloride (9CI)
681807-60-3
-
CYCLOPENTYL-(3,4,5-TRIMETHOXY-BENZYL)-AMINE HYDROCHLORIDE
1052525-88-8
-
2-Cyclopropylbenzenemethanamine hydrochloride Formula
118184-64-8
-
Des[4-(2-cycloproylMethoxy)] Betaxolol Hydrochloride Formula
464877-45-0
-
Ethanamine, 2-(decylthio)-, hydrochloride (1:1) Formula
36362-09-1
-
4,7-Dichloro-2-propylquinoline hydrochloride Structure
1204812-22-5
-
6,7-Dichloro-4-hydrazino-2-methylquinoline hydrochloride Structure
1170377-12-4
-
What is 2,8-Diazaspiro[4.5]decan-1-one, 2-[(4-bromophenyl)methyl]-, hydrochloride (1:1)
832710-56-2
-
What is 6,7-Dichloro-4-hydrazinoquinoline hydrochloride
1171843-02-9