D-HOMOPHENYLALANINE ETHYL ESTER HYDROC&

6-B: D-Homophenylalanine ethyl ester hydrochloride (6-A) (25.0 g, 102.5 mmol) is dissolved in 10% aqueous EtOH (500 mL). A catalytic amount of 5% Rh/C is added, and the reaction placed under an atmosphere of H2 (1000 psi), stirred, and heated to 50 C. After 18 h, the reaction is cooled to room temperature, the H2 gas supply is removed, and the vessel brought to atmospheric pressure. The catalyst is filtered through Celite, and the solvent removed in vacuo, to afford D-Homocyclohexylalanine ethyl ester hydrochloride as a white powder.

D-Homophenylalanine Ethyl Ester Hydrochloride is a useful research chemical.

D-Homophenylalanine ethyl ester hydrochloride may be used to synthesize (R)-2-amino-4-phenylbutan-1-ol, an intermediate for 2,6-bis[(4R)-4,5-dihydro-4-(2-phenylethyl)-2-oxazolyl]pyridine ligand.

Molecular Weight:243.73
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:243.1026065
Monoisotopic Mass:243.1026065
Topological Polar Surface Area:52.3
Heavy Atom Count:16
Complexity:188
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes