5,5′-Dithiobis[2-nitrobenzoic acid]
-
![5,5′-Dithiobis[2-nitrobenzoic acid] structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/73f4e4da553e4f63b6af175cedd60edb.png "5,5′-Dithiobis[2-nitrobenzoic acid]")
5,5′-Dithiobis[2-nitrobenzoic acid]
structure -
-
CAS No:
69-78-3
-
Formula:
C14H8N2O8S2
-
Chemical Name:
5,5′-Dithiobis[2-nitrobenzoic acid]
-
Synonyms:
Benzoic acid,3,3′-dithiobis[6-nitro-;3,3′-Dithiobis[6-nitrobenzoic acid];5,5′-Dithiobis[2-nitrobenzoic acid];DTNB;Ba 2767;Named reagents and solutions,Ellman's;2,2′-Dinitro-5,5′-dithiodibenzoic acid;Ellmans reagent;Reagents,Ellman's;3-Carboxy-4-nitrophenyl disulfide
- Categories:
-
CAS No:
Description
DTNB(Ellman’s Reag) is a chemical used to quantify the number or concentration of thiol groups in a sample; can be used for measuring low-molecular mass thiols such as glutathione in both pure solutions and biological samples, such as blood.
Dithionitrobenzoic acid is an organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups. It has a role as an indicator. It is a nitrobenzoic acid and an organic disulfide.|A standard reagent for the determination of reactive sulfhydryl groups by absorbance measurements. It is used primarily for the determination of sulfhydryl and disulfide groups in proteins. The color produced is due to the formation of a thio anion, 3-carboxyl-4-nitrothiophenolate.
5,5′-Dithiobis[2-nitrobenzoic acid] Basic Attributes
396.35
396.35
1896821
200-714-4
9BZQ3U62JX
DTXSID5058779
29309070
Characteristics
217
2.7
Yellow solid.
1.8±0.1 g/cm3
237-238 °C (decomp)
671.9°C at 760 mmHg
360.1±31.5 °C
1.769
soluble in water and ethanol.
Store at RT.
Safety Information
NONH for all modes of transport
3
36/37/38
26-36
DG9650000
Xi
Stable. Incompatible with strong bases, strong oxidizing agents.
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 51 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Chemical agents that react with SH groups. This is a chemically diverse group that is used for a variety of purposes. Among these are enzyme inhibition, enzyme reactivation or protection, and labelling. (See all compounds classified as Sulfhydryl Reagents.)
5,5'-Dithiobis(2-nitrobenzoic Acid)
5,5′-Dithiobis[2-nitrobenzoic acid] Use and Manufacturing
3,3'-Dithiobis[6-nitrobenzoic Acid is an membrane-impermeant thiol/disulfide exchange blocker. 3,3'-Dithiobis[6-nitrobenzoic Acid is also used to quantify the number or concentration of thiol groups in a sample.
Benzoic acid, 3,3'-dithiobis[6-nitro-: ACTIVE
Computed Properties
Molecular Weight:396.4
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:5
Exact Mass:395.97220756
Monoisotopic Mass:395.97220756
Topological Polar Surface Area:217
Heavy Atom Count:26
Complexity:528
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 5,5′-Dithiobis[2-nitrobenzoic acid]
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
1 YR
Business licensedTrader Supplier of Pharmaceutical intermediatesInquiryCAS No.: 69-78-3Grade: Chemical GradeContent: 99.0% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 69-78-3Grade: Pharmaceutical GradeContent: 99% -
![China]()
CN
1 YR
Business licensedTrader Supplier of synthetic reagents,catalysts,ligands,building blocks,solvents,analytical chemicals,biochemicals,reference standards
Learn More Other Chemicals
-
B,B′-(4,6-Dichloro-1,3-phenylene)bis[boronic acid]
1150114-65-0
-
3,3′-[[4-(Dimethylamino)phenyl]methylene]bis[6-hydroxy-5-methylbenzoic acid]
10143-03-0
-
3,3′-[2-Butyne-1,4-diylbis(oxy)]bis[2-hydroxy-1-propanesulfonic acid]
40456-31-3
-
Thiazolo[5,4-d]thiazole-2,5-diylbis[methoxybenzenesulfonic acid] Formula
66182-97-6
-
4,4′-[[1,1′-Biphenyl]-4,4′-diylbis(oxy)]bis[1,2-benzenedicarboxylic acid] Formula
26177-81-1
-
3,3′-[(2-Bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis[6-hydroxybenzoic acid] Formula
291766-06-8
-
3,3′-(Methylphosphinylidene)bis[propanoic acid] Structure
51805-41-5
-
3,3′-[Carbonylbis(imino-4,1-phenylene-2,1-diazenediyl)]bis[benzenesulfonic acid] Structure
34375-33-2
-
What is 2,2′-Oxybis[5-bromobenzoic acid]
1311197-85-9
-
What is P,P′-[(Propylimino)bis(methylene)]bis[phosphonic acid]
5995-27-7
5,5′-Dithiobis[2-nitrobenzoic acid]
SDSRequest for Quotation