1-Chloro-1-nitropropane

123.536

123.54

209-990-0

1423

8409

2810|1993

DTXSID2024797

LIQUID|Colorless liquid.

45.8

1.76120

1-chloro-1-nitropropane is a colorless liquid. Unpleasant odor. (USCG, 1999)

1.209 g/cm³ @ Temp: 20 °C

142 °C

(oc) 144°F

1.435

6 mg/L at 20 °C (quoted, Verschueren, 1983)

Vapour pressure, Pa at 25°C: 773.1

4.26

Acute oral LD 50 for mice 510 mg/kg (quoted, RTECS, 1985).

Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.

Unpleasant odor.

Slightly soluble in water [Lawry's].

Halogenated Organic Compounds

Explosive

1-CHLORO-1-NITROPROPANE is sensitive to heat (may be explosive). This chemical is incompatible with oxidizers. It will attack some forms of plastics, rubber and coatings (NTP, 1992). Combustible: May produce toxic gases, including nitrogen oxides, hydrogen chloride, and carbon monoxide. Will attack some plastics, rubber, and coatings (USCG, 1999).

9.90 eV

Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.

III

6.1(b)

UN 2810

20/22

TX5075000

Xn

Separated from strong oxidants and acids.

P261, P264, P270, P271, P301+P312, P304+P312, P304+P340, P312, P330, P501

H302

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.|1) BY ABSORBING...IN VERMICULITE, DRY SAND, EARTH OR SIMILAR MATERIAL & DISPOSING IN SECURED SANITARY LANDFILL. 2) BY ATOMIZING IN SUITABLE COMBUSTION CHAMBER EQUIPPED WITH APPROPRIATE EFFLUENT GAS CLEANING DEVICE.

Strong oxidizers, acids.

Combustible: May produce toxic gases, including nitrogen oxides, hydrogen chloride, and carbon monoxide. Will attack some plastics, rubber, and coatings. (USCG, 1999)|Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 62 °C explosive vapour/air mixtures may be formed.|Flammable - 2nd degree, Reactive - 3rd degree

|Warning|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P301+P312, P304+P312, P304+P340, P312, P330, and P501|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H227: Combustible liquid [Warning Flammable liquids]|P210, P261, P264, P270, P271, P280, P301+P312, P304+P340, P305+P351+P338, P312, P330, P337+P313, P370+P378, P403+P233, P403+P235, P405, and P501|P210, P260, P264, P270, P280, P301+P312, P305+P351+P338, P309+P311, P330, P332+P313, P337+P313, P370+P378, P403+P235, P405, and P501

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Keep people away; shut off ignition sources; call fire department; notify local health and pollution control agencies; protect water intakes. (USCG, 1999)

Skin: Wear appropriate personal protective clothing to prevent skin contact. Eyes: Wear appropriate eye protection to prevent eye contact. Wash skin: The worker should immediately wash the skin when it becomes contaminated. Remove: Work clothing that becomes wet or significantly contaminated should be removed and replaced. Change: No recommendation is made specifying the need for the worker to change clothing after the work shift. (NIOSH, 2016)|Recommendations for respirator selection. Max concn for use: 20 ppm. Respirator Class(es): Any supplied-air respirator. May require eye protection.|Recommendations for respirator selection. Max concn for use: 50 ppm. Respirator Class(es): Any supplied-air respirator operated in a continuous flow mode. May require eye protection. Any powered, air-purifying respirator with organic vapor cartridge(s). May require eye protection.|Recommendations for respirator selection. Max concn for use: 100 ppm. Respirator Class(es): Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s). Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister. Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s). May require eye protection. Any self-contained breathing apparatus with a full facepiece. Any supplied-air respirator with a full facepiece.|Recommendations for respirator selection. Condition: Emergency or planned entry into unknown concn or IDLH conditions: Respirator Class(es): Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure mode. Any supplied-air respirator with a full facepiece and operated in pressure-demand or other positive pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive pressure mode.|For more Personal Protective Equipment (PPE) (Complete) data for 1-CHLORO-1-NITROPROPANE (7 total), please visit the HSDB record page.|(See protection codes)

MODERATE, WHEN EXPOSED TO HEAT.

ALCOHOL FOAM, WATER, CARBON DIOXIDE, DRY CHEMICAL...

1) VENTILATE AREA OF SPILL OR LEAK. 2) FOR SMALL QUANTITIES, ABSORB ON PAPER TOWELS. EVAPORATE IN SAFE PLACE (SUCH AS FUME HOOD). ALLOW SUFFICIENT TIME FOR EVAPORATING VAPORS TO COMPLETELY CLEAR HOOD OR DUCTWORK. BURN PAPER IN SUITABLE LOCATION AWAY FROM COMBUSTIBLE MATERIALS. LARGE QUANTITIES CAN BE COLLECTED & ATOMIZED IN SUITABLE COMBUSTION CHAMBER EQUIPPED WITH APPROPRIATE EFFLUENT GAS CLEANING DEVICE. 3) MIX SPILL OF UP TO 1 GALLON WITH SODA ASH, SPRAY WITH WATER, LET STAND IN BUCKET WITH WATER FOR 2 HR, NEUTRALIZE WITH DIL HYDROCHLORIC ACID, FLUSH TO SEWER & WASH AREA OF SPILL WITH DETERGENT & SOLN.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|Most important methods of technical control to prevent hazards are general or local exhaust ventilation. General ventilation entails dilution of contaminated air with fresh air by fans or blowers in the working environment. ... The working room concentration should be maintained below the exposure limits by using both of these methods. If it is not possible to reduce excessive amounts of contaminants in the air by only the ventilation methods, enclosure of a process or segregation of personnel is recommended. /Chlorinated nitroparaffins/|The worker should immediately wash the skin when it becomes contaminated.|Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Strong irritant.

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 20 ppm (100 mg/cu m).|Vacated 1989 OSHA PEL TWA 2 ppm (10 mg/cu m) is still enforced in some states.

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 2 ppm (10 mg/cu m).

Personal protection: chemical protection suit including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Separated from strong oxidants and acids.

A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.

The substance is severely irritating to the eyes and respiratory tract. Inhalation of high concentrations of the vapour may cause lung oedema.

NO open flames, NO sparks and NO smoking. Above 62 °C use a closed system, ventilation and explosion-proof electrical equipment.

Use ventilation, local exhaust or breathing protection.

Protective gloves.

Wear safety goggles or eye protection in combination with breathing protection.

| 0 - Materials that, under emergency conditions, would offer no hazard beyond that of ordinary combustible materials.| 2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air.| 3 - Materials that in themselves are capable of detonation or explosive decomposition or explosive reaction but that require a strong initiating source or must be heated under confinement before initiation.| 3 - Materials that, under emergency conditions, can cause serious or permanent injury.

LD50 Rabbit oral between 50 and 100 mg/kg

4. 4= VERY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 50-500 MG/KG; BETWEEN 1 TEASPOONFUL & 1 OUNCE FOR 70 KG PERSON (150 LB).

LIQUID: Irritating to skin and eyes. Harmful if swallowed. (USCG, 1999)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)|(See procedures)

Fresh air, rest. Half-upright position. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

SEVERE PULMONARY EDEMA AFTER INHALATION OF VAPOR OR INGESTION OF LIQUID. NO SYSTEMIC EFFECTS FROM SKIN APPLICATION AND NO SIGNIFICANT SKIN IRRITATION.|CHEMICAL IS LACHRYMATORY (A TEAR GAS).

The substance can be absorbed into the body by inhalation and by ingestion.|inhalation, ingestion, skin and/or eye contact

In Animals: irritation eyes; pulmonary edema; liver, kidney, heart damage

Wheezing. Burning sensation. Cough. Shortness of breath.

Redness. Pain.

respiratory system, liver, kidneys, cardiovascular system, eyes

AIR: ADSORPTION ON CHROMOSORB 108, DESORPTION WITH ETHYL ACETATE, DETERMINED BY GC/FID (GAS CHROMATOGRAPHY WITH FLAME IONIZATION DETECTOR); RANGE: 51-206 MG/CU M.

Fire Hazards -> Flammable - 2nd degree, Reactive - 3rd degree