6-Carboxyfluorescein succinimidyl ester
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6-Carboxyfluorescein succinimidyl ester
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CAS No:
92557-81-8
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Formula:
C25H15NO9
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Chemical Name:
6-Carboxyfluorescein succinimidyl ester
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Synonyms:
Spiro[isobenzofuran-1(3H),9′-[9H]xanthene]-6-carboxylic acid,3′,6′-dihydroxy-3-oxo-,2,5-dioxo-1-pyrrolidinyl ester;2,5-Pyrrolidinedione,1-[[(3′,6′-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-6-yl)carbonyl]oxy]-;Spiro[isobenzofuran-1(3H),9′-[9H]xanthene],2,5-pyrrolidinedione deriv.;6-Carboxyfluorescein succinimidyl ester;Fluorescein-6-carboxylic acid N-succinimidyl ester;6-Carboxyfluorescein N-hydroxysuccinimide ester;(2,5-Dioxopyrrolidin-1-yl) 3′,6′-dihydroxy-1-oxospiro[2-benzofuran-3,9′-xanthene]-5-carboxylate;76608-16-7;142149-29-9;143908-32-1;199273-26-2;591742-83-5
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CAS No:
Description
6-FAM SE is another isomer of carboxyfluorescein. 6-FAM, SE is mainly used in sequencing of nucleic acids and labeling nucleotides.
6-carboxyfluorescein succinimidyl ester is an N-hydroxysuccinimide ester derived from 6-carboxyfluorescein. A fluorescent cell staining dye, it is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably to intracellular lysine residues. It has a role as a fluorochrome. It derives from a fluorescein (lactone form).
6-Carboxyfluorescein succinimidyl ester Use and Manufacturing
Intracellular pH probe. Fluorescent label for amines and alcohols. 6-Carboxyfluorescein-N-hydroxysuccinimide Ester is a commonly used fluorescent reagent for the labelling of peptides, proteins and nucleotides.
Computed Properties
Molecular Weight:473.4
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:3
Exact Mass:473.07468106
Monoisotopic Mass:473.07468106
Topological Polar Surface Area:140
Heavy Atom Count:35
Complexity:894
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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6-Carboxyfluorescein succinimidyl ester
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