Tricaprin
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Tricaprin
structure -
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CAS No:
621-71-6
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Formula:
C33H62O6
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Chemical Name:
Tricaprin
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Synonyms:
Decanoic acid,1,1′,1′′-(1,2,3-propanetriyl) ester;Decanoin,tri-;Decanoic acid,1,2,3-propanetriyl ester;Caprin,tri-;Tricaprin;Glycerol tridecanoate;Tricapric glyceride;Glycerol tricaprin;Tridecanoin;Capric acid triglyceride;Dynasan 110;Glyceryl tricaprate;Glycerol tricaprate;Glycerin tridecanoate;Panacet 1000;Tri(decanoyl)glycerol;Triglyceride DDD;Glycerin tricaprate;Actor M 2;Captex 1000;NSC 147475;Capric triglyceride;Decanoic acid triglyceride;Tricapryl glyceride;Glyceryl tridecanoate;2,3-Di(decanoyloxy)propyl decanoate;17263-37-5
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CAS No:
Description
Tricaprin (Glyceryl tridecanoate) is an orally available precursor of decanoic acid (DA) and can be hydrolyzed to DA. Tricaprin (Glyceryl tridecanoate) is a major component of medium chain triglyceride (MCT) with antiandrogen and antihyperglycemic properties[1].Tricaprin (Glyceryl tridecanoate) has a safe use in in foods, drugs, cosmetics as an additive[2].
Tricaprin Basic Attributes
554.853
554.84
210-702-0
O1PB8EU98M
147475
DTXSID1042651
C153424
3824909990
Characteristics
78.9
12.52
Solid
0.9±0.1 g/cm3
25 °C
578.6±17.0 °C at 760 mmHg
233.3±21.0 °C
1.461
1.334e-008 mg/L @ 25 °C (est)
-20ºC
Safety Information
UN 1282 3/PG 2
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R11
S26-S28
HE0100000
F,Xn
P210-P280-P305 + P351 + P338
H225-H302 + H312 + H332-H315-H319
Tricaprin Use and Manufacturing
Tricaprin is a highly refreshing, odorless oil derived from palm oil or coconut oil. It is widely used in food, medicine, cosmetics and other industries and has been proven to have no irritation to the human body. Tricaprin is a commercially available food supplement that promotes the breakdown of lipids by heart muscle cells. In addition to relieving troublesome and painful symptoms in these patients, Tricaprin significantly reduces the buildup of triglycerides in the blood vessels of the heart. Tricaprin is an oral precursor of capric acid (DA), a 10-carbon fatty acid that is the main component of medium-chain triglyceride oil and has potential anti-androgenic and anti-hyperglycemic properties. After oral administration, tridecyl glycerol hydrolyzes to DA, which binds to and partially activates the peroxisome proliferation-activating receptor (PPAR)-γ, as well as PPAR-α and PPAR-β/δ, but does not induce lipogenesis. In addition, tridecyl esters can improve insulin sensitivity and reduce androgen production. Tricaprin is used in cosmetics as an emollient and skin conditioner to help improve product texture and moisturizing properties. Tricaprin is usually extracted using thermal fractionation, and is suitable for oily skin due to its compatibility with human skin and does not clog pores, it has a non-greasy texture, and is added to creams or lotions to improve its elongation, lubricated and soft skin, and filters UV light. Tricaprin is lightweight and non-greasy, making it ideal for skin care products such as creams and lotions. This ingredient is also widely used in hair care products as it can tone the hair dry without making the hair dry heavier. In addition, Tricaprin enhances the spreadability of the formula, leaving skin and hair with a smooth, silky feel. The chemical formula for this component is C33H62O6. Tricaprin is naturally derived and versatile, and is valued in the cosmetics industry for its ability to improve the overall sensory experience of skin and hair care products.
Decanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester: ACTIVE
Lipids -> Glycerolipids [GL] -> Triradylglycerols [GL03] -> Triacylglycerols [GL0301]|Cosmetics -> Emollient; Skin conditioning; Solvent
Computed Properties
Molecular Weight:554.8
XLogP3:12.2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:32
Exact Mass:554.45463969
Monoisotopic Mass:554.45463969
Topological Polar Surface Area:78.9
Heavy Atom Count:39
Complexity:543
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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