Lead carbonate (PbCO3)

267.21

267.96100

209-943-4

43M0P24L2B

0999

Colorless, rhombic crystals

28369917

63.2

-2.82780

White Powder

6.6 g/cm³

315 °C (decomp)

333.6ºC at 760mmHg

169.8ºC

2.08

soluble in acid and alkali. Insoluble in water, alcohol and ammonia.Solubility in water, g/100ml: 0.0001

Store below +30°C.

Oral-guinea pig LDL0: 1000 mg/kg

Combustible, the fire emits spicy spicy stimulating smoke

Transformed in hot water to the basic carbonate, 2PbCO3.Pb(OH)2|Divalent lead has a strong affinity for inorganic ions containing oxygen (eg, carbonate) or sulfur (sulfide). Lead can also complex with electron rich ligands in many organic cmpd such as amino acids, proteins, and humic acid.|Lead is derived from the decay of radon. /Inorganic lead/|Natural lead is a mixture of four stable isotopes: Pb-204 (1.4%), Pb-206 (25.2%), Pb-207 (21.7%) and Pb-208 (51.7%). Lead isotopes are the end-products of each of the three series of naturally occurring radioactive elements: Pb-206 for the uranium series, Pb-207 for the actinium series and Pb-208 for the thorium series. Forty-three other isotopes of lead, all of which are radioactive, are recognized.

III

6.1

UN 3077 9/PG 3

3

61-20/22-33-50/53-62-45

53-45-60-61

OF9275000

T,N

Warehouse low temperature, ventilated, dry

Stable. Incompatible with strong acids, strong oxidizing agents.

P201-P260-P280-P301 + P312 + P330-P308 + P313

H302 + H332-H350-H360Df-H373-H410

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D008, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste. /Lead/|In view of the economic importance of lead and its latent danger, it is desirable that lead residues be routed to a recovery plant to a great extent. Treatment with nitric acid to produce lead nitrate and subsequent precipitation of lead sulfide by introducing hydrogen sulfide into the lead nitrate soln is suitable as a standard method for recovering lead from impure residues and various lead cmpd. The filtered lead sulfide can then be directed to the recovery plant. Where lead carbonate occurs in small, distributed amt after use, disposal along with refuse and inert waste will be safe in most cases. It should nevertheless be pointed out in a precautionary sense that lead carbonate is not insoluble. Recommendable methods: Recycling, precipitation, solidification, & landfill. Not recommendable method: Thermal destruction.

... Burns fiercely in fluorine.

National Toxicology Program. Eleventh Report on Carcinogens (2005). The Report on Carcinogens is an informational scientific and public health document that identifies and discusses substances (including agents, mixtures, or exposure circumstances) that may pose a carcinogenic hazard to human health. Lead and Lead Compounds are listed as reasonably anticipated to be human carcinogens. /Lead and Lead Compounds/[Available from, as of July 31, 2009: http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s101lead.pdf]|IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Vol 87 Inorganic and Organic Lead Compounds Geneva: World Health Organization, International Agency for Research on Cancer, (2006). IARC Monographs provide critical reviews of data on carcinogenicity for agents to which humans are known to be exposed and on specific exposure situations.

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P273, P281, P301+P312, P304+P312, P304+P340, P308+P313, P312, P314, P330, P391, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.|Aggregated GHS information provided by 56 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H332: Harmful if inhaled [Warning Acute toxicity, inhalation]|P201, P202, P260, P261, P271, P281, P304+P312, P304+P340, P308+P313, P312, P314, P405, and P501|H350: May cause cancer [Danger Carcinogenicity]|P201, P202, P260, P264, P270, P281, P307+P311, P308+P313, P314, P321, P405, and P501

In case of fire in the surroundings, use appropriate extinguishing media.

Wear appropriate personal protective clothing to prevent skin contact. /Lead/|Wear appropriate eye protection to prevent eye contact. /Lead/|Respirator Recommendations: Up to 0.5 mg/cu m. /Lead/ [Table#3416]|Respirator Recommendations: Up to 1.25 mg/cu m. /Lead/ [Table#3417]|For more Personal Protective Equipment (PPE) (Complete) data for LEAD CARBONATE (9 total), please visit the HSDB record page.

Ignites spontaneously and burns fiercely in fluorine.

SRP: Contaminated protective clothing should be segregated in a manner so that results in no direct personal contact by personnel who handle, dispose of, or clean the clothing. Quality assurance procedures to confirm the efficacy of the cleaning procedures should be implemented prior to the decontaminated protective clothing being returned for reuse by the workers. Contaminated clothing (including shoes/socks) should not be taken home at end of shift, but should remain at employee's place of work for cleaning.|SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.|The worker should wash daily at the end of each work shift, and prior to eating, drinking, smoking, etc. /Lead/|Work clothing that becomes wet or significantly contaminated should be removed or replaced. /Lead/|Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises. /Lead/

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Permissible Exposure Limit: The employer shall assure that no employee is exposed to lead at concentrations greater than 50 ug/cu m of air averaged over an 8-hr period. If an employee is exposed to lead for more than 8 hr in any work day, the permissible exposure limit, as a TWA for that day, shall be reduced according to the following formula: Maximum permissible limit (in ug/cu m)=400 divided by the number of hours worked in the day. /Lead, inorganic, as Pb/|The employer shall remove an employee from work having an exposure to lead at or above the action level on each occasion that a periodic and a follow-up blood sampling test conducted pursuant to this section indicate that the employee's blood lead level is at or above 60 ug/100 g of whole blood; and, the employer shall remove an employee from work having an exposure to lead at or above the action level on each occasion that the average of the last three blood sampling tests conducted pursuant to this section (or the average of all blood sampling tests conducted over the previous six (6) months, whichever is longer) indicates that the employee's blood lead level is at or above 50 ug/100 g of whole blood; provided, however, that an employee need not be removed if the last blood sampling test indicates a blood lead level at or below 40 ug/100 g of whole blood. ... The employer shall return an employee to his or her former job status: ... when two consecutive blood sampling tests indicate that the employee's blood lead level is at or below 40 ug/100 g of whole blood. ... The employer shall provide to an employee up to eighteen (18) months of medical removal protection benefits on each occasion that an employee is removed from exposure to lead or otherwise limited pursuant to this section. /Lead, inorganic, as Pb/|Permissible Exposure Limit: The employer shall assure that no employee is exposed to lead at concentrations greater than 50 ug/cu m of air averaged over an 8-hr period. If an employee is exposed to lead for more than 8 hr in any work day, the permissible exposure limit, as a TWA for that day, shall be reduced according to the following formula: Maximum permissible limit (in ug/cu m)=400 divided by the number of hours worked in the day. /Lead, inorganic, as Pb; Shipyard Employment/|The employer shall remove an employee from work having an exposure to lead at or above the action level on each occasion that a periodic and a follow-up blood sampling test conducted pursuant to this section indicate that the employee's blood lead level is at or above 60 ug/100 g of whole blood; and, the employer shall remove an employee from work having an exposure to lead at or above the action level on each occasion that the average of the last three blood sampling tests conducted pursuant to this section (or the average of all blood sampling tests conducted over the previous six (6) months, whichever is longer) indicates that the employee's blood lead level is at or above 50 ug/100 g of whole blood; provided, however, that an employee need not be removed if the last blood sampling test indicates a blood lead level at or below 40 ug/100 g of whole blood. ... The employer shall return an employee to his or her former job status: ... when two consecutive blood sampling tests indicate that the employee's blood lead level is at or below 40 ug/100 g of whole blood. ... The employer shall provide to an employee up to eighteen (18) months of medical removal protection benefits on each occasion that an employee is removed from exposure to lead or otherwise limited pursuant to this section. /Lead, inorganic, as Pb; Shipyard Empolyment/|For more OSHA Standards (Complete) data for LEAD CARBONATE (6 total), please visit the HSDB record page.

NIOSH considers "Lead" to mean metallic lead, lead oxides, and lead salts (including organic salts such as lead soaps but excluding lead arsenate).|Recommended Exposure Limit: 10 hr Time-Weighted Avg: 0.050 mg/cu m /Lead/|Air concentrations should be maintained so that worker blood lead remains less than 0.06 mg Pb/100 g of whole blood.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Separated from food and feedstuffs and incompatible materials. See Chemical Dangers.

Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

The substance may have effects on the blood, bone marrow, central nervous system, peripheral nervous system and kidneys. This may result in anaemia, haemolysis, encephalopathy (for example, convulsions), peripheral nerve disease and kidney impairment. Causes toxicity to human reproduction or development.

AVOID ALL CONTACT!

Use local exhaust or breathing protection.

Protective gloves.

Wear safety spectacles.

National primary and secondary ambient air quality standards for lead and its compounds, measured as elemental lead by a reference method based on appendix G to this part, or by an equivalent method, are: 1.5 micrograms per cubic meter, maximum arithmetic mean averaged over a calendar quarter. /Lead and its compounds, as Pb/|Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Lead compounds are included on this list. /Lead compounds/

D008; A solid waste containing lead may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Lead/

D008; A solid waste containing lead may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Lead/|The Environmental Protection Agency is ... /promulgated/ regulations concerning ground-water monitoring with regard to screening suspected contamination at land based hazardous waste treatment, storage, and disposal facilities. ... /There are/ new requirements to analyze for a specified core list of chemicals plus those chemicals specified by the Regional Administrator on a site-specific basis. ... /Total lead (all species) is included on this list./ /Total lead (all species)/

SOIL: In a calcareous soil, PbSO4 and PbCO3 were shown to account for <5% of the total lead content, whereas in road side dust, PbSO4, elemental lead, Pb3O4, PbO.PbSO4 and 2PbCO3.Pb(OH)2 were present in high quantities(1). Extractable forms of lead carbonate in Haplorthods and Haplumbrepts sandy and loamy soils from Tarnowskie Gory in Southwest Poland ranged from 0.5-78.1 mg/kg (10 samples) and 1.0-650 mg/kg (14 samples), respectively(2).

SOURCE DOMINATED: Lead carbonate is found in the exhaust of automobiles using leaded gasoline the composition of airborne lead particles in car exhaust 18 hr after collection was 13.8% PbCO3 and 29.6% 2PbO.PbCO3(1). The composition of airborne lead particles at three sites (compound - near a road (%), 400 yds from a road (%), rural site (%): PbCO3 -15.6, 14.6, 30.2; 2PbO.PbCO3 - 37.9, 21.3, 27.5(1).

moderately toxic

In a series of experiments, the toxicity of lead to worms in soil was determined following the draft OECD earthworm reproduction toxicity protocol except that lead was added as solid lead nitrate, carbonate and sulfide ... The compounds were added to the test soil to give lead concn of 625-12 500 ug Pb/g of soil. Calculated toxicities of the lead decreased in the order nitrate > carbonate > sulfide, the same order as the decrease in the solubility of the metal compounds used. The 7-day LC50 ... for the nitrate was 5,321 +/- 275 ug Pb/g of soil, and this did not change with time. The LC50 values for carbonate and sulfide could not be determined at the concn ranges used. The only parameter sensitive enough to distinguish the toxicities of the three compounds was cocoon (egg) production. The EC50s for cocoon production (the concn to produce a 50% reduction in cocoon production) were 993, 8,604, and 10,246 pg Pb/g of soil for lead nitrate, carbonate, and sulfide, respectively ...|... Female mallards /were dosed/ with 100 mg lead/kg diet. This was added as a mixture of 43 mg/kg lead carbonate, 37 mg/kg lead oxide, and 49 mg/kg lead sulfate, each salt contributing one-third of the total lead. No significant effect on eggshell thickness was found when it was measured on days 76 and 85 of treatment. When lead was added to the diet along with DDE at 40 mg/kg, lead did not increase the effect of the organochlorine on shell thickness.|To determine if additive or synergistic toxic effects would occur, adult male rats were exposed orally to lead carbonate (2,000 mg/kg) for 9 days before trichloroethylene (TCE), 2,000 mg/kg, was given concurrently for an additional 7 days. Comparisons were made with groups of vehicle-treated rats and rats given only lead or only TCE. Potential neurotoxicity was evaluated by using the Functional Observational Battery (FOB) recommended for neurotoxicity screening. Rats were sacrificed on day 16, and brain, testes, spleen, kidney/adrenals, heart, and liver weighed and observed for pathological changes. Results of the FOB indicated that lead carbonate was more responsible than TCE for changes observed. Additive or synergistic neurotoxicities were not noted. Histological examination of the kidney from lead-treated rats revealed inclusions, an increased incidence of coagulated proteins, and tubular dilation that was generally more severe in the medullary segments. Gastric and testicular necrosis were found in rats given lead carbonate both with and without TCE (15/20 and 6/20 treated, respectively). The results suggest that, even when given concurrently, the toxicities of lead carbonate and TCE are expressed only as though one toxicant was given.|Toxic amt of zinc prevented the development of clinical signs of lead poisoning in horses 2-3 wk old which were fed for 30 wk with a diet containing 3.5-108.5 mg/kg lead carbonate and 24.7-181.7 mg/kg zinc oxide.|The addn of lead carbonate at the level of 30 ppm to the ration increased the lead concn in whole blood, liver, kidney, vertebra, rib, but not in metacarpal diaphysis or epiphysis, brain, lung, or muscle in young horses. Five groups of foals were fed rations that differed in calcium & phosphorus content for 26 wk. The liver was the only organ where the lead values from foals fed rations containing the least amt of calcium were significantly higher.

/BIRDS and MAMMALS/ ... Female mallards /were dosed/ with 100 mg lead/kg diet. This was added as a mixture of 43 mg/kg lead carbonate, 37 mg/kg lead oxide, and 49 mg/kg lead sulfate, each salt contributing one-third of the total lead. No significant effect on eggshell thickness was found when it was measured on days 76 and 85 of treatment. When lead was added to the diet along with DDE at 40 mg/kg, lead did not increase the effect of the organochlorine on shell thickness.|/OTHER TERRESTRIAL SPECIES/ In a series of experiments, the toxicity of lead to worms in soil was determined following the draft OECD earthworm reproduction toxicity protocol except that lead was added as solid lead nitrate, carbonate and sulfide ... The compounds were added to the test soil to give lead concn of 625-12 500 ug Pb/g of soil. Calculated toxicities of the lead decreased in the order nitrate > carbonate > sulfide, the same order as the decrease in the solubility of the metal compounds used. The 7-day LC50 ... for the nitrate was 5,321 +/- 275 ug Pb/g of soil, and this did not change with time. The LC50 values for carbonate and sulfide could not be determined at the concn ranges used. The only parameter sensitive enough to distinguish the toxicities of the three compounds was cocoon (egg) production. The EC50s for cocoon production (the concn to produce a 50% reduction in cocoon production) were 993, 8,604, and 10,246 pg Pb/g of soil for lead nitrate, carbonate, and sulfide, respectively ...

Extent of occurrence of /lead/ in earth's crust is about 15 g/ton, also expressed as 0.002% (depth of crust: 16 km). Occurs chiefly as sulfide in galena, other minerals include anglesite (PbSO4), cerussite (PbCO3), mimetite (PbCl2.3Pb3-(AsO4)2) and pyromorphite [PbCl2.3Pb3(PO4)2)].|Cerrusite is lead carbonate(1). Lead carbonate (PbCO3) may also be formed from lead compounds released into the atmosphere or natural waters(1,2).

Lead carbonate may be released to the environment during the mining and processing of cerrusite ore. However most of the lead ore mined in the USA is galena, PbS(1). Runoff water containing lead carbonate may result from water sprays used to control dust in lead mining operations.|Lead carbonate (PbCO3) may be released during its manufacture for use as basic lead carbonate in white exterior paint and ceramic glazes(1). Since PbCO3 tends to form naturally when lead is released into the atmosphere or natural waters, any source of lead (Pb) emission is a potential source of PbCO3. In particular, lead carbonate is found in the exhaust of automobiles using leaded gasoline(2). PbCO3 may also form when Pb containing wastewater or runoff is discharged into natural waters.

TERRESTRIAL FATE: Lead carbonate should not leach in soil because of its relative insolubility. In soil, lead is expected to convert to more insoluble forms such as PbSO4, Pb3(PO4)2, PbS, and PbO(1). It also forms complexes with organic matter and clay minerals that limits its mobility.|AQUATIC FATE: In solution, Pb++ will form ligands. The dominant complexes formed will be a function of pH(2). In freshwater systems, the most important ligands are HCO3, CO3, OH and (OH)2, whereas in seawater they are Cl, CO3, (OH), (OH)2, Cl2, and Cl3(1). Lead carbonate will partially precipitate depending on the pH and other ions in solution.|ATMOSPHERIC FATE: While lead carbonate may be released to the atmosphere during its production and use, most of the compounds will be formed in the air from other lead compounds. In the atmosphere, it will be in particulate matter and be subject to washout and gravitational settling. (SRC)

Organolead compounds undergo photolysis and other reactions in the atmosphere to form lead carbonates, oxycarbonates, and oxides; once these compounds encounter components of the soil, further reactions can occur, resulting in a complex variety of lead compounds(1).

According to the 2006 TSCA Inventory Update Report, the number of workers reasonably likely to be exposed in the industrial manufacturing, processing, and use for lead carbonate is 100 to 999 persons; the data may be greatly underestimated(1).|NIOSH (NOES Survey 1981-1983) has statistically estimated that 2,791 workers (772 of these were female) were potentially exposed to lead carbonate in the US(1). Occupational exposure to lead carbonate may occur through inhalation and dermal contact with this compound at workplaces where lead is produced or used; since lead carbonate may be formed naturally when lead or its compounds are released into the atmosphere, exposure may occur near sources of lead emissions such as mining, ore processing, smelting and refining sites, as well as from leaded gasoline exhaust. The lead industry employs about 7,000 people; two thirds of this number are employed in mining and concentrating operations(2). Monitoring data indicate that the general population may be exposed to lead carbonate via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound or other products containing lead(SRC).|People living in the vicinity of lead sources such as emissions from motor vehicles, mining operations, and smelters may be exposed to lead carbonate because lead compounds may be converted to the carbonate in the atmosphere. This lead is primarily in airborne particulate matter that settles out on plants and in water and may subsequently be ingested. Lead carbonate may similarly occur in drinking water since lead may form carbonates with dissolved carbon dioxide. While the solubility of lead carbonate is not high and adsorption through the lung is slight, it will dissolve in the stomach after which it may be absorbed in moderate quantities. (SRC)

IVE: This study was designed to evaluate the source of Pb in blood of ... 49 children (48 < 5 years of age) along with 18 adults (> 20 years of age) ... . Mean PbB level of the children was 7.5 ug/dL (range, 1.5-25.7 ug/dL; n = 49; geometric mean, 6.6 ug/dL), with four children whose PbB was > 12 ug/dL. The isotopic data for blood samples lay around two distinct arrays. The blood of all children analyzed for Pb isotopes contained a contribution of Pb from the Magellan mine, which for young children ranged from 27% up to 93% (mean, 64%; median, 71%). Subtraction of the ore component gave a mean background PbB of 2.3 ug/dL. Several children whose PbB was > 9 ug/dL and most of the older subjects have complex sources of Pb. ... The death of the birds acted as a sentinel event; otherwise, the exposure of the community, arising from such a toxic form of Pb, could have been tragic ...|Adult male dogs were given daily doses of 34.1 mg and 68.2 mg basic lead carbonate for 60 days. Ratio of urinary lead excretion to total lead admin was very small, 0.24 & 0.09% respectively. 98.7 & 98.9% respectively of total lead admin was fecally excreted. Urinary and fecal excretions totalled 98.4 & 97.9% respectively. The highest concn was found in teeth and bones, followed by bone marrow, hair, and trachea. /Basic lead carbonate/

In rat pups chronically exposed to lead carbonate, biochemical changes incl diminished potassium chloride (KCl) evoked release of exogenous (3)h-dopamine from brain slices, and suppression of dopamine receptor mediated activation of adenylate cyclase in neostriatal homogenates. Results are discussed in relation to the possible mechanisms assoc with lead evoked neurochemical changes and the role that each effect may play in the lead induced alterations of locomotor activity.

Lead carbonate is available in USA as a commercial grade with minimum purity of 99.0%. Impurities typically present include: nitrate & nitrite (as HNO3), 0.005% max; zinc, 30 mg/kg max; chloride, 20 mg/kg max; cadmium, 20 mg/kg max; and iron, 20 mg/kg max. Lead carbonate in Japan has min purity of 99.0%. It may contain the following impurities: water, 1% max; matter sol in water, 0.5% max; & matter insol in acetic acid, 0.1% max.

Fresh air, rest.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Lead and related compounds/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Administer activated charcoal ... . /Lead and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or is in severe respiratory distress. Moderate hyperventilation (20 respiration per minute) may be beneficial for increased intracranial pressure. Start IV administration of 0.9% saline (NS) or lactated Ringer's (LR) /SRP: "To keep open", minimal flow rate/. For hypotension ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Lead and related compounds/|Treatment. Emergency and supportive measures. Treat seizures and coma if they occur. Provide adequate fluids to maintain urine flow but avoid overhydration, which may aggravate cerebral edema. Avoid phenothiazines for delirium, as they may lower the seizure threshold. Patients with increased intracranial pressure may benefit from corticosteroids and mannitol. /Lead/|For more Antidote and Emergency Treatment (Complete) data for LEAD CARBONATE (6 total), please visit the HSDB record page.

/SIGNS AND SYMPTOMS/ Human systemic effects by ingestion: gastrointestinal contractions, jaundice, brain degenerative changes, convulsions, nausea or vomiting.|/SIGNS AND SYMPTOMS/ ... A publication ... described mild and severe forms of lead poisoning from observations on 405 potters (235 females and 170 males) exposed to fine lead carbonate. The major signs and symptoms of plumbism were acute pains in the head, disturbances of vision, tremors, suppression of urine, and eliptiform convulsions.|/SIGNS AND SYMPTOMS/ The authors, by means of documentary research, study the possibility that the physical and psychic symptoms of Vincent van Gogh may have been due to chronic lead poisoning. The technique and materials used by Van Gogh are analyzed as the cause of repeated exposure to lead as well as the possible means of penetration of the metal ... The authors conclude that the excessive and continuous use by Van Gogh of pigments which were highly toxic due to their high lead content, such as white lead (lead carbonate) and yellow chrome (lead chromium), could have /given/ rise to a clinical condition of chronic lead poisoning. This type of poisoning coincides with the clinical symptoms Van Gogh describes in his autographed letters: initial debilitation, stomatitis with loss of teeth, recurring abdominal pains, anemia (with a "plumbic" skin tone), neuropathy of the radial and saturnine encephalopathy including epileptic crises, progressive character changes and periods of delirium ...|/SURVEILLANCE/ ... In late 2006, the seaside community in Esperance, Western Australia, was alerted to thousands of native bird species dying. The source of the lead was thought to derive from the handling of Pb carbonate concentrate from the Magellan mine through the port of Esperance, begun in July 2005. Concern was expressed for the impact of this process on the community. ... IVE: This study was designed to evaluate the source of Pb in blood of ... 49 children (48 < 5 years of age) along with 18 adults (> 20 years of age) ... . Mean PbB level of the children was 7.5 ug/dL (range, 1.5-25.7 ug/dL; n = 49; geometric mean, 6.6 ug/dL), with four children whose PbB was > 12 ug/dL. The isotopic data for blood samples lay around two distinct arrays. The blood of all children analyzed for Pb isotopes contained a contribution of Pb from the Magellan mine, which for young children ranged from 27% up to 93% (mean, 64%; median, 71%). Subtraction of the ore component gave a mean background PbB of 2.3 ug/dL. Several children whose PbB was > 9 ug/dL and most of the older subjects have complex sources of Pb. ... The death of the birds acted as a sentinel event; otherwise, the exposure of the community, arising from such a toxic form of Pb, could have been tragic ...

cerussite

The substance can be absorbed into the body by inhalation and by ingestion.

All other basic inorganic chemical manufacturing|Carbonic acid, lead(2+) salt (1:1): ACTIVE|Carbonic acid, lead(2+) salt (1:?): INACTIVE|Lead carbonate itself has very limited industrial use; however one basic lead carbonate, lead dihydroxydicarbonate (2PbCO3.Pb(OH)2), containing 62-66% lead carbonate, is used commercially.