β-Asarone
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β-Asarone
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CAS No:
5273-86-9
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Formula:
C12H16O3
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Chemical Name:
β-Asarone
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Synonyms:
Benzene,1,2,4-trimethoxy-5-(1Z)-1-propen-1-yl-;Benzene,1,2,4-trimethoxy-5-propenyl-,(Z)-;β-Asarone;Benzene,1,2,4-trimethoxy-5-(1-propenyl)-,(Z)-;Benzene,1,2,4-trimethoxy-5-(1Z)-1-propenyl-;1,2,4-Trimethoxy-5-(1Z)-1-propen-1-ylbenzene;cis-β-Asarone;cis-Isoasarone;cis-Asarone;(Z)-Asarone;(Z)-Azarone
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CAS No:
Description
Beta-asarone is a major ingredient of Acorus tatarinowii Schott, penetrates blood brain barrier, with the properties ofimmunosuppression, central nervous system inhibition, sedation, and hypothermy. Beta-asarone protects against Parkinson’s disease[1].
Characteristics
27.69000
2.98
Colorless crystals
1.0±0.1 g/cm3
296℃
>230 °F
1.526
-20°C
Reference value: Oral-mouse LD50: 418 mg/kg; Abdominal-mouse LD50: 310 mg/kg
Flammable; burning produces irritating fumes
Drug Function and Efficacy
It antagonizes histamine and acetylcholine, relieves bronchospasm and has an anti-asthmatic effect; it has a strong inhibitory effect on the cough center; it causes increased secretions, thins thick sputum, reduces sputum viscosity, and makes it easier to cough up; it has a similar effect to aminophylline in relaxing bronchial smooth muscles; it increases the electrical stimulation threshold of the cerebral cortex, inhibits synaptic conduction of electrical stimulation and the spread of epileptic electricity.
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