Brilliant Green

482.63

482.223938

3901207

211-190-1

G0L543D370

5011

DTXSID1048700

Minute, glistening, golden crystals|Green crystalline powder

32041300

92.29000

6.48360

Metallic green Powder/Solid

1.1016 (rough estimate)

210 °C (decomp)

H2O: 100 G/L (25 ºC)

Store at RT.

Oral-rat LDL0: 10 mg/kg; Abdominal cavity-mouse LDL0: 5 mg/kg

Flammable; burning produces toxic nitrogen oxides, sulfur oxides and ammonia fumes

C.I. Basic Green 1 has indicator properties with a visual-transition interval of pH 0.0 (yellow) to pH 2.6 (green).

II

6.1(a)

2811

3

22-36-36/37/38-20/21/22

26-39-36-24/25

BP6825000

Xn

Ventilated, low temperature and dry

Stable. Incompatible with strong oxidizing agents, reducing agents.

P305 + P351 + P338

H302-H319

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Incompatible with anionic, oxidizing and reducing substances. Incompatible with aqueous suspensions of bentonite.

Hatch KL, Maibach HI; J Am Acad Dermatol 32 (4): 631-9 (1995). The literature concerning textile dye dermatitis published during the last decade was reviewed. ... The 10 new dye allergens /included/ ... the basic dye brilliant green. ...|USEPA; Chemical Profile: C.I. Basic Green 1 (1985). Chemical safety information sheet /details toxicological information concerning this dye/.

|Danger|H301 (13.16%): Toxic if swallowed [Danger Acute toxicity, oral]|P260, P261, P264, P270, P272, P273, P280, P301+P310, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P391, P405, and P501|Aggregated GHS information provided by 158 companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P264, P270, P280, P281, P301+P312, P305+P351+P338, P308+P313, P310, P330, P405, and P501

A skin irritant

most toxic

LDLo Rat intraperitoneal 8 mg/kg|LDLo Mouse oral 25 mg/kg|LDLo Mouse intraperitoneal 5 mg/kg|LDLo Mouse intravenous 3 mg/kg|For more Non-Human Toxicity Values (Complete) data for C.I. BASIC GREEN 1 (6 total), please visit the HSDB record page.

C.I. Basic Green 1's production and use as a dye, in the preparation of spirit inks, wood stains and pigments, and in antiseptic solutions used for neonatal nurseries(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 13(SRC), determined from a measured water solubility(2) and a recommended regression-derived equation(3), indicates that C.I. Basic Green 1 will have very high mobility in soil(SRC). Due to the ionic nature of C.I. Basic Green 1, the retention of the dye by ion-exchange processes(4,SRC), particularly on clay surfaces, and adsorption at mineral surfaces such as geothite(5,SRC), may slow down or prevent leaching(SRC). As C.I. Basic Green 1 is an ionic compound, volatilization of this compound will not be important from moist soil surfaces(4,SRC). Based on limited data, C.I. Basic Green 1 is expected to be resistant to aerobic biodegradation in soil(SRC). In an aqueous screening test, only 1.3% of the theoretical BOD was reached in 5 days(6).|AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 13(SRC), determined from a measured water solubility(2) and a recommended regression-derived equation(1), indicates that C.I. Basic Green 1 should not adsorb to suspended solids and sediment in water(SRC). However, due to the ionic nature of C.I. Basic Green 1, the retention of the dye by ion-exchange processes(3,SRC), particularly on clay surfaces, and adsorption at mineral surfaces such as geothite(4,SRC), may lead to increased adsorption on some surfaces(SRC). As C.I. Basic Green 1 is an ionic compound, volatilization from water surfaces is not expected(3,SRC). According to a classification scheme(5), an estimated BCF value of 2(1,SRC), from a measured water solubility(2), suggests that bioconcentration in aquatic organisms is low(SRC). Based on limited data, C.I. Basic Green 1 is expected to be resistant to aerobic biodegradation in water(SRC). In an aqueous screening test, only 1.3% of the theoretical BOD was reached in 5 days(6).|ATMOSPHERIC FATE: The ionic state of C.I. Basic Green 1 makes this compound essentially non-volatile(1,SRC); therefore, this compound should exist in the particulate phase in the ambient atmosphere. Particulate-phase C.I. Basic Green 1 may be physically removed from the air, mainly by wet deposition(SRC).

An estimated BCF value of 2 was calculated for C.I. Basic Green 1(SRC), using a measured water solubility of 40,000 mg/l(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).

The Koc of C.I. Basic Green 1 is estimated as approximately 13(SRC), using a measured water solubility of 40,000 mg/l(1) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this estimated Koc value suggests that C.I. Basic Green 1 has very high mobility in soil(SRC). Due to the ionic nature of the dye, the retention of C.I. Basic Green 1 by ion-exchange processes(4,SRC), particularly on clay surfaces and adsorption at mineral surfaces such as geothite(5,SRC), may slow down or prevent leaching(SRC).

Since C.I. Basic Green 1 is an ionic compound, evaporation from water and moist soil surfaces will not be important(1,SRC).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 42,531 workers (28,804 of these are female) are potentially exposed to C.I. Basic Green 1 in the US(1). Occupational exposure may be through inhalation of dust particles and dermal contact with this compound at workplaces where C.I. Basic Green 1 is produced or used. The general population may be exposed to C.I. Basic Green 1 via dermal contact with products containing C.I. Basic Green 1(SRC).

Anti-Infective Agents, Local; Dyes|Brilliant green is a disinfectant effective against vegetative Gram-positive bacteria but less effective against Gram-negative organisms and ineffective against acid-fast bacteria and bacterial spores. Its activity is greatly reduced in the presence of serum ... It has been applied as a 0.05-0.1% solution in water or hyperosmotic saline in the treatment of infected wounds or burns. A solution of brilliant green 0.5% and crystal violet 0.5% has been used for disinfecting the skin.|Intestinal anthelmintic, wound antiseptic and in the treatment of mycotic infections.

Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects. (See all compounds classified as Anti-Infective Agents, Local.)|Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)

Brilliant green ... has been employed topically on the skin as an antiseptic, but in contact with the eye is severely injurious. In one instance an attempt to treat conjunctivitis with 1% solution of this dye resulted in destructive keratitis with hypopyon and terminated in bilateral blindness due to corneal opacification.|Ingestion causes diarrhea & abdominal pain.|Eczema, cross-reaction with gentian violet and malachite green.

(4-(4-(diethylamino)-alpha-phenylbenzylidene)-2,5-cyclohexadien-1-ylidene)diethylammonium sulfate

Ethanaminium, N-[4-[[4-(diethylamino)phenyl]phenylmethylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-, sulfate (1:1): ACTIVE

Cosmetics -> Hair dyeing