N-Formyl-N-hydroxyglycine
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N-Formyl-N-hydroxyglycine
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CAS No:
689-13-4
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Formula:
C3H5NO4
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Chemical Name:
N-Formyl-N-hydroxyglycine
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Synonyms:
Glycine,N-formyl-N-hydroxy-;N-Formyl-N-hydroxyglycine;NSC 521778;Hadacidin;Hadacidine;NFHAA;N-Hydroxyformamidoacetic acid
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CAS No:
Description
ChEBI: A monocarboxylic acid that is N-hydroxyglycine in which the hydrogen attached to the nitrogen is replaced by a formyl group. It was originally isolated from cultures of Penicillium frequentans.
Hadacidin is a monocarboxylic acid that is N-hydroxyglycine in which the hydrogen attached to the nitrogen is replaced by a formyl group. It was originally isolated from cultures of Penicillium frequentans. It has a role as a teratogenic agent, an antineoplastic agent, an antimicrobial agent and a Penicillium metabolite. It is a monocarboxylic acid, a N-hydroxy-alpha-amino-acid and an aldehyde.
Drug Information
Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms. (See all compounds classified as Antibiotics, Antineoplastic.)|An agent that causes the production of physical defects in the developing embryo. (See all compounds classified as Teratogens.)
hadacidin
N-Formyl-N-hydroxyglycine Use and Manufacturing
Hadacidin is known for its ability to inhibit the proliferation of cells often seen with cancers, thus allowing it to be an anti-cancer agent. It is an inhibitor of adenylsuccinate synthetase.
Computed Properties
Molecular Weight:119.08
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:119.02185764
Monoisotopic Mass:119.02185764
Topological Polar Surface Area:77.8
Heavy Atom Count:8
Complexity:102
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes