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Home > Encyclopedia > 2-Hydroxychalcone

2-Hydroxychalcone

2-Hydroxychalcone structure

2-Hydroxychalcone 

structure
  • CAS No:

    644-78-0

  • Formula:

    C15H12O2

  • Chemical Name:

    2-Hydroxychalcone

  • Synonyms:

    2-Propen-1-one,3-(2-hydroxyphenyl)-1-phenyl-;Chalcone,2-hydroxy-;3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one;2-Hydroxychalcone;3-(o-Hydroxyphenyl)acrylophenone;o-Hydroxystyryl phenyl ketone;1-Phenyl-3-(2-hydroxyphenyl)-2-propenone;Salicylideneacetophenone;NSC 37432;NSC 640539;3-(2-Hydroxyphenyl)-1-phenylpropenone

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB[1][2][3].

2-Hydroxychalcone Basic Attributes

224.25

224.25

2049134

211-422-1

2914501900

Characteristics

37.3

3.28830

1.191g/cm3

153-154 °C

396.566ºC at 760 mmHg

169.35ºC

1.654

Safety Information

3

36/37/38

26-36

Xi

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

H315

Computed Properties

Molecular Weight:224.25
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:224.083729621
Monoisotopic Mass:224.083729621
Topological Polar Surface Area:37.3
Heavy Atom Count:17
Complexity:277
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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