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2-Hydroxychalcone

2-Hydroxychalcone structure

CAS No:
644-78-0
Formula:
C15H12O2
Chemical Name:
2-Hydroxychalcone
Synonyms:
2-Propen-1-one,3-(2-hydroxyphenyl)-1-phenyl-;Chalcone,2-hydroxy-;3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one;2-Hydroxychalcone;3-(o-Hydroxyphenyl)acrylophenone;o-Hydroxystyryl phenyl ketone;1-Phenyl-3-(2-hydroxyphenyl)-2-propenone;Salicylideneacetophenone;NSC 37432;NSC 640539;3-(2-Hydroxyphenyl)-1-phenylpropenone
Categories:
Biochemical Engineering > Plant Extracts

Description

2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB[1][2][3].

2-Hydroxychalcone Basic Attributes

Molecular Weight：

224.25

Exact Mass：

224.25

BRN：

2049134

EC Number：

211-422-1

HScode：

2914501900

Characteristics

PSA：

37.3

XLogP3：

3.28830

Density：

1.191g/cm3

Melting Point：

153-154 °C

Boiling Point：

396.566ºC at 760 mmHg

Flash Point：

169.35ºC

Refractive Index：

1.654

Safety Information

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36

Marks：

Precautionary statement(s)：

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

Computed Properties

Molecular Weight:224.25
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:224.083729621
Monoisotopic Mass:224.083729621
Topological Polar Surface Area:37.3
Heavy Atom Count:17
Complexity:277
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 644-78-0

Grade: Pharmaceutical Grade

Content: 99%

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Guide of 2-Hydroxychalcone

Description
Basic Attributes
Characteristics
Safety Information
Computed Properties
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2-Hydroxychalcone

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