L-Homocysteine
-
L-Homocysteine
structure -
-
CAS No:
6027-13-0
-
Formula:
C4H9NO2S
-
Chemical Name:
L-Homocysteine
-
Synonyms:
L-Homocysteine;Butyric acid,2-amino-4-mercapto-,L-;Butanoic acid,2-amino-4-mercapto-,(S)-;2-Amino-4-mercapto-L-butyric acid;Homocysteine;(S)-2-Amino-4-mercaptobutanoic acid;(S)-Homocysteine;2-Amino-4-mercaptobutyric acid;NSC 43117;454-28-4;1867-00-1
- Categories:
-
CAS No:
Description
L-Homocysteine, a homocysteine metabolite, is a homocysteine that has L configuration. L-Homocysteine induces upregulation of cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2].
Solid
L-homocysteine is a homocysteine that has L configuration. It has a role as a mouse metabolite. It is a homocysteine and a serine family amino acid. It is a conjugate acid of a L-homocysteinate. It is a tautomer of a L-homocysteine zwitterion.|Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine.|Homocysteine is an amino acid derivative and homolog of cysteine containing an additional methylene bridge. Homocysteine is a product of methionine metabolism and elevated plasma levels are associated with cardiovascular disease, Alzheimer disease and several metabolic diseases.|A thiol-containing amino acid formed by a demethylation of METHIONINE.
Characteristics
64.3
-3.4
Solid
1.3±0.1 g/cm3
232.5 °C
299.7°C at 760 mmHg
135.0±25.9 °C
1.538
148 mg/mL
-20°C
130.53 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|159.62 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|124 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|130.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|143.6 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|127.6 Ų [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
Safety Information
NONH for all modes of transport
3
22
22-24/25
Xn
P264, P270, P301+P312, P330, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory.
L-Homocysteine Use and Manufacturing
L-Homocysteine is the hydrolysis product of adenosine (A280400), a purine nucleoside. Metabolic fate of L-Homocysteine is converted back to L-Methionine( M260440) via tetrahydrofolate.
Computed Properties
Molecular Weight:135.19
XLogP3:-3.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:135.03539970
Monoisotopic Mass:135.03539970
Topological Polar Surface Area:64.3
Heavy Atom Count:8
Complexity:86.1
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of L-Homocysteine
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
4 YRS
Business licensedTrader Supplier of Basic chemicals,Specialty chemicals,Raw materials&Intermediates,Fine chemicals,Pharmaceutical intermediates
Learn More Other Chemicals
-
L-Homocysteine thiolactone hydrochloride
31828-68-9
-
L-Glutamic acid, N-[3-carboxy-2-(carboxymethyl)-2-hydroxy-1-oxopropyl]-
73590-26-8
-
1-chloro-6-Methyl-5-nitroisoquinoline
943606-84-6
-
2-chloro-N-(2-oxothiolan-3-yl)acetamide Formula
84611-22-3
-
N-[(Phenylmethoxy)carbonyl]-L-phenylalanylglycine Formula
13122-99-1
-
(αR)-α-[(Methoxycarbonyl)amino]benzeneacetic acid Formula
50890-96-5
-
3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide Structure
461000-66-8
-
5-(4-Hydroxyphenyl)-2,4-imidazolidinedione Structure
2420-17-9
-
What is γ-Aminobenzenepropanol
14593-04-5
-
What is 2-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
170491-63-1