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Narbomycin

Narbomycin structure

CAS No:
6036-25-5
Formula:
C28H47NO7
Chemical Name:
Narbomycin
Synonyms:
Erythromycin,3-de[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-10-demethyl-6,11,12-trideoxy-3-oxo-,(10E)-;Narbomycin;Picromycin,12-deoxy-;Oxacyclotetradec-11-ene-2,4,10-trione,14-ethyl-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-,(3R,5R,6S,7S,9R,11E,13R,14R)-;(10E)-3-De[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-10-demethyl-6,11,12-trideoxy-3-oxoerythromycin;Norbomycin;Norbomycine;Antibiotic B 62169B;1414-30-8;27656-75-3;874385-83-8;957792-17-5
Categories:
Organic Chemistry > Lactones

Description

ChEBI: A macrolide antibiotic that is narbonolide having a 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residue attached at position 6. It is biosynthesised by Streptomyces venezuelae.

Narbomycin is a macrolide antibiotic that is narbonolide having a 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residue attached at position 6. It is biosynthesised by Streptomyces venezuelae. It has a role as a bacterial metabolite. It is a macrolide antibiotic, a monosaccharide derivative and an enone. It derives from a narbonolide. It is a conjugate base of a narbomycin(1+).

Narbomycin Basic Attributes

Molecular Weight：

509.684

Exact Mass：

509.68

UNII：

024664144V

Characteristics

PSA：

102

XLogP3：

4.4

Melting Point：

113.5-115.0 °C

Toxicity：

LD50 s.c. in mice: 500 mg/kg (Corbaz)

Drug Information

MeSH Entry Terms：

narbomycin

Computed Properties

Molecular Weight:509.7
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:509.33525284
Monoisotopic Mass:509.33525284
Topological Polar Surface Area:102
Heavy Atom Count:36
Complexity:797
Defined Atom Stereocenter Count:11
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes